tamsulosin
aka - Flomax
Research
20 / 388 results
research Tamsulosin Treatment for Benign Prostatic Hyperplasia and Risk of Severe Hypotension in Men Aged 40-85 Years in the United States: Risk Window Analyses Using Between and Within Patient Methodology
This study observed a temporal association between tamsulosin use for benign prostatic hyperplasia and an increased risk of severe hypotension requiring hospital admission during the first eight weeks of treatment initiation and restart.
research Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia
This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.
research Measurement of Tamsulosin in Human Serum by Liquid Chromatography–Tandem Mass Spectrometry
This study developed and validated a sensitive LC-MS/MS method for quantifying tamsulosin in human serum, achieving high analyte recovery and demonstrating applicability in clinical research for benign prostatic hyperplasia.
research Pharmacokinetic Interaction of Finasteride With Tamsulosin Hydrochloride: An Open-Label, Randomized, Three-Period Crossover Study in Healthy Chinese Male Volunteers
This study observed that coadministration of finasteride and tamsulosin in healthy Chinese males appears unlikely to result in a clinically significant pharmacokinetic interaction.
research Efficacy and Tolerability of 6-Month Treatment with Tamsulosin Plus Hexanic Extract of Serenoa Repens Versus Tamsulosin Plus 5-Alpha-Reductase Inhibitors for Moderate-to-Severe LUTS-BPH Patients: Results of a Paired Matched Clinical Study
This study found that for men with moderate-to-severe LUTS/BPH, 6 months of treatment with tamsulosin plus the hexanic extract of S. repens was as effective as tamsulosin plus a 5-alpha-reductase inhibitor but had better tolerability.
research Simultaneous Determination of Finasteride and Tamsulosin in Combined Dosage Form by Using RP-HPLC Method
This study successfully developed and validated a reverse-phase HPLC method for accurately determining finasteride and tamsulosin simultaneously in bulk and pharmaceutical formulations.
research Analysis of Differences in Medication Adherence in the Method of Administration of Tamsulosin and Finasteride Combination Therapy for Benign Prostatic Hyperplasia
This study concluded that packaging tamsulosin and finasteride together for co-administration in patients with benign prostatic hyperplasia improves medication adherence compared to packaging each drug separately.
research Chromatographic Methods for Determination of Finasteride and Tamsulosin Hydrochloride in Presence of Finasteride Degradation Product
This study developed two sensitive chromatographic methods for determining finasteride and tamsulosin hydrochloride in pharmaceutical forms, validated against International Conference on Harmonisation guidelines.
research Complications of Cataract Surgery in Wistar Rats Undergoing Treatment with Tamsulosin
In this study, researchers found that discontinuing tamsulosin for one month before cataract surgery in rats reduces manifestations of intraoperative floppy iris syndrome, suggesting alternative preoperative treatments may be beneficial.
research Research on Intraoperative Iris Behavior in Rabbits Treated with Tamsulosin and Finasteride
This study found an increased risk of intraoperative iris billowing in rabbits treated with finasteride, similar to those treated with tamsulosin, suggesting further research in humans is needed.
research Simultaneous Estimation of Finasteride and Tamsulosin Hydrochloride in Combined Dosage Forms by RP-HPLC-PDA Method
This study developed and validated an RP-HPLC-PDA method for accurately estimating Tamsulosin and Finasteride in bulk and tablet forms, achieving precise detection and linearity within specified concentration ranges.
research Second Derivative Spectrophotometric Method for Simultaneous Determination of Tamsulosin and Finasteride in Pharmaceutical Formulations
This study developed and validated a second derivative spectrophotometric method for accurately estimating tamsulosin and finasteride in bulk and pharmaceutical formulations.
research UV Spectrophotometric Method for Simultaneous Determination of Finasteride and Tamsulosin in Combined Dosage Form
This study developed and validated a UV spectrophotometric method for accurately measuring finasteride and tamsulosin in solutions and tablets, demonstrating good sensitivity and precision.
research Comparison of Combination Therapy With Tamsulosin and Dutasteride or Finasteride in Patients With Benign Prostatic Hyperplasia: A Randomized Clinical Trial
This study found that dutasteride improved maximum urinary flow rate more effectively than finasteride when used in combination therapy with tamsulosin for treating benign prostatic hyperplasia over six months.
research Spectrophotometric and Stability Indicating RP-HPLC-PDA Method for Simultaneous Determination of Finasteride and Tamsulosin in Combined Tablet Dosage Form
This study developed and validated ultraviolet spectrophotometric and reversed phase high performance liquid chromatographic methods for simultaneously estimating Tamsulosin and Finasteride in tablet form, showing statistical validation and effectiveness in pharmaceutical analysis.
research RP-HPLC Assay Method for Simultaneous Estimation of Tamsulosin Hydrochloride and Finasteride in Pharmaceutical Dosage Form
This study successfully developed and validated a sensitive and precise liquid chromatography method for simultaneously estimating tamsulosine hydrochloride and finasteride in tablets, showing high accuracy and minimal interference from excipients.
research Tamsulosin Versus Finasteride: Effect on Bother and Urinary Flow
Tamsulosin works faster, but both drugs have similar effects after 6 months.
research Risk of Poor Glycemic Control in Tamsulosin Versus Finasteride Users with Type 2 Diabetes Mellitus
This study found no significant difference in the risk of poor glycemic control between men with type 2 diabetes using tamsulosin and those using finasteride.
research Response Surface Methodology Approach to Formulate and Optimize the Bilayer Combination Tablet of Tamsulosin and Finasteride
In this study, the researchers developed and optimized a bilayer tablet containing Tamsulosin and Finasteride, achieving sustained and immediate drug release with favorable release kinetics, including first-order and anomalous diffusion mechanisms, through in vitro testing.
research Is the Sulfonamide Group of Tamsulosin the Main Factor in the Pathophysiology of Floppy Iris Syndrome?
This study hypothesizes that the sulfonamide group in tamsulosin might contribute to its association with intraoperative floppy iris syndrome.