Saw Palmetto
aka - Serenoa repens
🛒 Where to find Saw Palmetto
Tracking 12 topical products and 5 oral products by companies like Amazon, Dr.FORHAIR, Hims, Jack Health and Keeps. View all 17 products »Saw Palmetto, scientifically known as Serenoa repens, is a small palm tree native to the southeastern United States. Its history of use spans back to the Native American populations, who prized its berries for their nutritional and medicinal properties. Traditionally utilized for urinary and reproductive issues, saw palmetto has been extensively researched for its potential health benefits, which include applications in treating benign prostatic hyperplasia (BPH) and hair loss.
The role of saw palmetto in alopecia, particularly androgenetic alopecia (AGA), has garnered interest due to its purported mechanism of action. It is believed that saw palmetto works by inhibiting 5-alpha reductase, an enzyme responsible for converting testosterone into dihydrotestosterone (DHT). DHT is a known contributor to both AGA and prostate enlargement. By potentially reducing DHT levels, saw palmetto could slow or reduce hair loss and provide a natural alternative to synthetic 5-alpha reductase inhibitors like finasteride.
Research on saw palmetto's efficacy for hair loss has produced mixed results. Some studies suggest modest improvements in hair count and quality with few reported side effects, positioning it as a complementary treatment for those seeking natural remedies. For instance, a systematic review highlighted improvements in hair quality and density in patients with AGA and telogen effluvium when using saw palmetto supplements. However, the research landscape is marked by variability in study design, sample size, and outcome measures, which has led to calls for more rigorous clinical trials to fully understand its benefits and mechanisms of action.
The sentiment within the community is mostly skeptical, especially when compared to more established treatments like minoxidil and finasteride. Others share anecdotal evidence of positive experiences, suggesting that saw palmetto may play a role in their hair loss treatment regimen, particularly for those seeking less aggressive therapy or wishing to avoid the side effects associated with pharmaceutical options.
In summary, Saw Palmetto is a natural remedy purported to reduce hair loss by inhibiting the enzyme responsible for DHT production. While some research and anecdotal evidence support its use in treating alopecia, the scientific community calls for more definitive studies to establish its efficacy and safety profile.
Research
20 / 1000+ results
research A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome

research Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract

research Sensitization to Saw Palmetto and Minoxidil in Separate Topical Extemporaneous Treatments for Androgenetic Alopecia

research Natural Hair Supplement: Friend or Foe? Saw Palmetto, A Systematic Review in Alopecia

research Saw Palmetto Extract Inhibits Metastasis and Antiangiogenesis Through STAT3 Signal Pathway in Glioma Cells

research Effect of Saw Palmetto Supplements on Androgen-Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth

research Saw Palmetto and Finasteride in the Treatment of Category-III Prostatitis/Chronic Pelvic Pain Syndrome

research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
research Determination of the Potency of a Novel Saw Palmetto Supercritical CO2 Extract for 5α-Reductase Isoform II Inhibition Using a Cell-Free In Vitro Test System

research Homologous Recombination Induced by Doxazosin Mesylate and Saw Palmetto in the Drosophila Wing-Spot Test

research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part I
research Development of Nanoliposomes Loaded with Carbon Dioxide Serenoa Repens (Saw Palmetto) Extract

research Influence of Saw Palmetto and Pygeum Africana Extracts on the Urinary Concentrations of Endogenous Anabolic Steroids: Relevance to Doping Analysis

research The Use of Serenoa Repens (Saw Palmetto) in Hair Care Products

research Saw Palmetto (Serenoa Repens) in Androgenic Alopecia: An Effective Phytotherapy

research Hair Loss (Alopecia) Treatment Using Rosemary Oil, Peppermint Oil, Amla Oil, and Saw Palmetto: A Students’ Survey

research Oral and Topical Administration of Standardized Saw Palmetto Oil Reduces Hair Fall and Improves Hair Growth in Androgenetic Alopecia Subjects: A 16-Week Randomized, Placebo-Controlled Study

research The Role of 5-Alpha-Reductase Inhibition in Suppressing Progression of Male Androgenetic Alopecia and the Potential Application of Saw Palmetto Extracts

research A Comparative Study of Topical Procapil With Platelet-Rich Plasma Therapy Versus Topical Redensyl, Saw Palmetto, and Biotin With Platelet-Rich Plasma Therapy in the Treatment of Androgenetic Alopecia
