Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid, and Saw Palmetto Extract

    Sridar V. Chittur, Brian A. Parr, G Marcovici
    Studysummary This study found that a composition including Serenoa repens extract and anti-inflammatory agents effectively suppressed inflammation-related gene expression in a keratinocyte model, suggesting a potential dual strategy for treating androgenetic alopecia.
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    Research cited in this study 12

    1. A Cell-Based System for Screening Hair Growth-Promoting Agents Archives of Dermatological Research · 2009
    2. L-Carnitine-L-Tartrate Promotes Human Hair Growth In Vitro Experimental Dermatology · 2007
    3. Obesity and Low-Grade Inflammation Among Young Finnish Men With Early-Onset Alopecia Dermatology · 2007
    4. The Additive Effects of Minoxidil and Retinol on Human Hair Growth In Vitro Biological & Pharmaceutical Bulletin · 2007
    5. The Hair Growth Promoting Effect of Asiasari Radix Extract and Its Molecular Regulation Journal of Dermatological Science · 2005
    6. Finasteride in the Treatment of Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2004
    7. Stress Inhibits Hair Growth in Mice by Inducing Premature Catagen Development and Harmful Perifollicular Inflammatory Events via Neuropeptide Substance P-Dependent Pathways American Journal of Pathology · 2003
    8. Association Between Smoking and Hair Loss: Another Opportunity for Health Education Against Smoking? Dermatology · 2003
    9. Molecular Mechanisms of Androgenetic Alopecia Experimental Gerontology · 2002
    10. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-Alpha-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002
    11. Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia Expert Opinion on Investigational Drugs · 1999
    12. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998

    Related research 2

    1. Keratins of the Human Hair Follicle International review of cytology · 2005
    2. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001