A Cell-Based System for Screening Hair Growth-Promoting Agents

    March 2009 in “ Archives of Dermatological Research ”
    Sungran Huh, Jongsung Lee, Eunsun Jung … Deokhoon Park
    Studysummary This study suggests that apigenin may stimulate hair growth by downregulating TGF-ß1 gene expression in human epidermal keratinocytes and promoting hair follicle elongation in a rat hair follicle culture.
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    Research cited in this study 7

    1. Establishment of SV40T-Transformed Human Dermal Papilla Cells and Identification of Dihydrotestosterone-Regulated Genes by cDNA Microarray Journal of Dermatological Science · 2007
    2. Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    3. Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth ˜The œFASEB journal · 2002
    4. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    5. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997
    6. Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture Journal of interferon & cytokine research · 1997
    7. Human Hair Growth In Vitro: A Model for the Study of Hair Follicle Biology Journal of Dermatological Science · 1994

    Related research 4

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    2. Study on Hair Follicle Formation Induced by Dermal Papilla Cells Chinese Journal of Reparative and Reconstructive Surgery · 2003
    3. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001
    4. Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998