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    Establishment of SV40T-Transformed Human Dermal Papilla Cells and Identification of Dihydrotestosterone-Regulated Genes by cDNA Microarray

    Soo-Jin Park, Mi Hee Kwack, Eun Jee Chung … Young Kwan Sung
    Studysummary This study identified several genes regulated by dihydrotestosterone in an SV40T-transformed human dermal papilla cell line, which may play a role in androgen-mediated hair growth regulation.
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    Research cited in this study 11

    1. Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells Journal of Investigative Dermatology · 2006
    2. Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis Journal of Dermatological Science · 2004
    3. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    4. Identification of Androgen-Regulated Genes in SV40-Transformed Human Hair Dermal Papilla Cells Journal of dermatological science · 2003
    5. Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth ˜The œFASEB journal · 2002
    6. Simple and Rapid Method to Isolate and Culture Follicular Papillae from Human Scalp Hair Follicles Experimental Dermatology · 2002
    7. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    8. Immortalized Rat Whisker Dermal Papilla Cells Cooperate with Mouse Immature Hair Follicle Buds to Activate Type IV Procollagenases in Collagen Matrix Coculture: Correlation with Ability to Promote Hair Follicle Development in Nude Mouse Grafts Journal of Investigative Dermatology · 1995
    9. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995
    10. Transfection of Rat Dermal Papilla Cells with a Gene Encoding a Temperature-Sensitive Polyomavirus Large T Antigen Generates Cell Lines Retaining a Differentiated Phenotype Journal of Cell Science · 1994
    11. Human Hair Growth In Vitro Journal of Cell Science · 1990

    Related research 8

    1. Identification of a New Plant Extract for Androgenic Alopecia Treatment Using a Non-Radioactive Human Hair Dermal Papilla Cell-Based Assay BMC Complementary and Alternative Medicine · 2015
    2. Androgen Actions on the Human Hair Follicle: Perspectives Experimental Dermatology · 2012
    3. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    4. Relation Between Dermal Papilla Cells and Androgenetic Alopecia International Journal of Dermatology and Venereology · 2010
    5. Establishment of SV40T-Transformed Human Dermal Papilla Cells and Identification of Dihydrotestosterone-Regulated Genes by cDNA Microarray Journal of Dermatological Science · 2007
    6. Male Androgenetic Alopecia The Journal of Men's Health & Gender · 2004
    7. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    8. Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992