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GlossaryDecorin

small proteoglycan that regulates collagen fiber formation

Decorin is a small proteoglycan found in the extracellular matrix of connective tissues. It plays a crucial role in regulating collagen fibrillogenesis, which is the process of collagen fiber formation, and helps maintain the structural integrity of tissues. Additionally, decorin has been shown to influence cell growth and wound healing, making it significant in both normal physiological processes and pathological conditions.

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research Extracellular Proteoglycan Decorin Maintains Human Hair Follicle Stem Cells

11 citations, October 2018 in “The Journal of Dermatology”

Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.

research Decorin Promotes Proliferation and Migration of ORS Keratinocytes and Maintains Hair Anagen in Mice

10 citations, August 2018 in “Experimental Dermatology”

Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.

research A Newly Discovered Linkage Between Proteoglycans and Hair Biology: Decorin Acts as an Anagen Inducer

10 citations, August 2014 in “Experimental Dermatology”

Decorin, a protein, may help start hair growth and could be used to treat hair loss.

research Cashmere Growth Control in Liaoning Cashmere Goat by Ovarian Carcinoma Immunoreactive Antigen-Like Protein 2 and Decorin Genes

7 citations, March 2018 in “Asian-Australasian journal of animal sciences”

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

Establishment of SV40T-Transformed Human Dermal Papilla Cells and Identification of Dihydrotestosterone-Regulated Genes by cDNA Microarray

research Establishment of SV40T-Transformed Human Dermal Papilla Cells and Identification of Dihydrotestosterone-Regulated Genes by cDNA Microarray

13 citations, June 2007 in “Journal of Dermatological Science”

Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.

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