research Extracellular proteoglycan decorin maintains human hair follicle stem cells
This study suggests that decorin may help maintain hair follicle stem cells and its reduced expression could contribute to age-related hair loss.
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research Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice
This study found that DECORIN promotes the proliferation and migration of outer root sheath keratinocytes in vitro and maintains the hair anagen phase in mice.
research A newly discovered linkage between proteoglycans and hair biology: decorin acts as an anagen inducer
The study found that exogenous decorin administration accelerated the anagen phase and delayed the catagen transition, suggesting it may act as a positive regulator of the hair cycle.
research Cashmere growth control in Liaoning cashmere goat by ovarian carcinoma immunoreactive antigen-like protein 2 and decorin genes
This study observed that the OCIAD2 and DCN genes in Liaoning cashmere goats have opposite effects on hair growth by interacting with the TGF-β signaling pathway, influencing follicle morphogenesis and periodic changes.
research Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis
This study found that decorin treatment significantly enhances dermal papilla cell proliferation, promoting hair follicle growth by influencing the SMAD3/TGF-β signaling pathway through exosomal miR-129–2-3p, which may aid in novel strategies for treating hair disorders and enhancing wool production.
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