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GlossaryKeratinocyte Growth Factor (FGF7)

stimulates skin and hair cell growth and repair

Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a protein that plays a crucial role in the growth and repair of skin and hair. It specifically stimulates the proliferation and differentiation of keratinocytes, which are the primary cells found in the outer layer of the skin and hair follicles. This makes KGF important in wound healing and potentially beneficial in treating conditions like alopecia.

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research BFNB Enhances Hair Growth in C57BL/6 Mice Through the Induction of EGF and FGF7 Factors and the PI3K-AKT-Beta-Catenin Pathway

2 citations, July 2023 in “International Journal of Molecular Sciences”

BFNB could be a promising treatment for hair growth.

research Kyoh Rocket Leaf Extract Regulates Proliferation and VEGF and FGF7 Expression in Human Dermal Follicle Papilla Cells

March 2025 in “Molecules”

Kyoh® rocket leaf extract may promote hair growth naturally with fewer side effects.

research FGF7-Dependent Inhibition of Human Hair Growth by an Osteopontin-Derived Peptide: A Novel Solution for Hirsutism and Hypertrichosis

April 2018 in “Journal of Investigative Dermatology”

A new peptide, FOL-005, may help treat excessive hair growth by reducing a hair growth promoter, FGF7.

research Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair

314 citations, April 2010 in “Developmental Cell”

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

research FGF Family: From Drug Development to Clinical Application

103 citations, June 2018 in “International Journal of Molecular Sciences”

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

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community GT20029 and PP405 the new fin and min that we been waiting for ?

in Chat 36 upvotes 1 month ago

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

community Comprehensive Microneedling Guide

in Microneedling 289 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.