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    Did you mean Androgen Signaling?
    GlossaryAndrogen Signaling

    process where male hormones bind to cell receptors

    Androgen signaling refers to the process by which androgens, which are male hormones like testosterone, bind to specific receptors in cells to regulate various biological functions. This signaling pathway is crucial for the development and maintenance of male characteristics, but it also plays a role in conditions like androgenetic alopecia (pattern hair loss) by affecting hair follicle health and growth.

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      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 2 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community 4600 - result 9 month - Dr. Carman

      in Progress Pictures  255 upvotes 9 months ago
      A user shared their 9-month post-hair transplant results with 4600 grafts, using only Nourkin hair vitamins, Vitamin D, and B12, and expressed satisfaction. The replies debated the necessity of medications like finasteride and minoxidil for maintaining hair health.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  123 upvotes 11 months ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  6 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  739 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.