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    Did you mean Androgen Signaling?
    Glossary Androgen Signaling

    process where male hormones bind to cell receptors

    Androgen signaling refers to the process by which androgens, which are male hormones like testosterone, bind to specific receptors in cells to regulate various biological functions. This signaling pathway is crucial for the development and maintenance of male characteristics, but it also plays a role in conditions like androgenetic alopecia (pattern hair loss) by affecting hair follicle health and growth.

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    Research 30 of 1000+

    1. 592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation Journal of Investigative Dermatology · 2019
    2. Hair follicle stem cell differentiation is inhibited through cross‐talk between Wnt/β‐catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia British Journal of Dermatology · 2012 · 95 citations
    3. Ginsenoside CK inhibits androgenetic alopecia by regulating Wnt/β‐catenin and p53 signaling pathways in AGA mice Food frontiers · 2023
    4. The Hair Follicle and Hair Loss: A Review of DHT, Inflammation, Oxidative Stress, Vascular Signalling and the Biological Pathways Behind Hair Growth Zenodo (CERN European Organization for Nuclear Research) · 2026
    5. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men Cell Stem Cell · 2020 · 139 citations
    6. Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways InTech eBooks · 2017 · 1 citations
    7. Therapeutic Potentiality of Celtis choseniana Nakai on Androgenic Alopecia through Repression of Androgen Action and Modulation of Wnt/β-catenin Signaling Natural product sciences · 2023
    8. Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway Journal of Translational Internal Medicine · 2024
    9. Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome Frontiers in endocrinology · 2023
    10. New insights into molecular signaling pathways and current advancements in prostate cancer diagnostics & therapeutics Frontiers in Oncology · 2023
    11. Therapeutic Effects of Modified Changfa Zirong Powder on Androgenetic Alopecia through the Wnt/β-Catenin Signaling Pathway Phytomedicine · 2025
    12. Taurine Alleviates Androgenetic Alopecia in Male C57BL/6 Mice by Modulating Hair Follicle Cycle and Related Signaling Pathways PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS · 2025
    13. Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla Journal of Dermatological Science · 2010 · 122 citations
    14. Selective androgen receptor modulators: a critical appraisal Frontiers in Endocrinology · 2025 · 2 citations
    15. Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells BMC Genomic Data · 2022 · 1 citations
    16. Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia Molecular and Cellular Endocrinology · 2016 · 47 citations
    17. Regulatory pathways implicated in male androgenetic alopecia pathogenesis British Journal of Dermatology · 2017
    18. The Rise in Adrenal Androgen Biosynthesis: Adrenarche Seminars in Reproductive Medicine · 2004 · 173 citations
    19. 0980 Tanshinone capsule enhances hair follicle regeneration in a mouse model of androgenetic alopecia via IGF1 and Wnt/β-catenin pathway Journal of Investigative Dermatology · 2026
    20. Discovery of (2<i>S</i>)-<i>N</i>-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment Journal of Medicinal Chemistry · 2023
    21. Androgens and androgen receptor action in skin and hair follicles Molecular and Cellular Endocrinology · 2017 · 100 citations
    22. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    23. Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep Cell Death and Disease · 2020 · 23 citations
    24. Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2018 · 18 citations
    25. Targets to treat androgen excess in polycystic ovary syndrome Expert Opinion on Therapeutic Targets · 2015 · 14 citations
    26. Novel complex of cosmetic ingredients with promising action in preventing hair loss and follicular aging through mechanism involving enrichment of <i>WNT</i>/signaling, mitochondrial activity, and stem cells maintenance Journal of Cosmetic Dermatology · 2020 · 8 citations
    27. 1406 DETECTION OF MEMBRANE ANDROGEN-BINDING SITE IN LIVING RAT PROSTATE AND EVALUATION OF ITS ROLE IN PROSTATE BLOOD FLOW REGULATION The Journal of Urology · 2010
    28. 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance Journal of Investigative Dermatology · 2016
    29. PD59-09 PHOSPHODIESTERASE INHIBITORS COULD REVERSE THE PROLIFERATION OF BPH EPITHELIAL CELLS INDUCED BY CD8+ T CELLS IN LOW ANDROGEN CONDITION The Journal of Urology · 2018
    30. Androgen actions on the human hair follicle: perspectives Experimental Dermatology · 2012 · 115 citations