Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data

    July 2018 in “ Journal of Investigative Dermatology ”
    Lara M. Hochfeld, Andreas Keller, Thomas Anhalt … Stefanie Heilmann-Heimbach
    Studysummary This article reviews the genetic research on male androgenetic alopecia, highlighting that over 300 associated risk variants have been identified, with unclear mechanisms of action.
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    Research cited in this study 9

    1. Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells Stem Cell Reports · 2017
    2. Adipocyte-Myofibroblast Transition as a Possible Pathophysiological Step in Androgenetic Alopecia Experimental Dermatology · 2017
    3. Androgenetic Alopecia: A Review Endocrine · 2017
    4. Genetic Prediction of Male Pattern Baldness PLoS Genetics · 2017
    5. Hunting the Genes in Male-Pattern Alopecia: How Important Are They, How Close Are We and What Will They Tell Us? Experimental Dermatology · 2016
    6. Local Circadian Clock Gates Cell Cycle Progression of Transient Amplifying Cells During Regenerative Hair Cycling Proceedings of the National Academy of Sciences of the United States of America · 2013
    7. Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis Journal of Investigative Dermatology · 2007
    8. Conditional Expression of the ErbB2 Oncogene Elicits Reversible Hyperplasia in Stratified Epithelia and Up-Regulation of TGFα Expression in Transgenic Mice Oncogene · 1999
    9. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999