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    Local Circadian Clock Gates Cell Cycle Progression of Transient Amplifying Cells During Regenerative Hair Cycling

    May 2013 in “ Proceedings of the National Academy of Sciences of the United States of America ”
    Maksim V. Plikus, Christopher Vollmers, Damon de la Cruz … Cheng‐Ming Chuong
    Studysummary This study discovered that the circadian clock influences hair follicle regeneration, making hair grow faster in the morning and causing more radiation-induced hair loss in the morning compared to the evening.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. Brain And Muscle Arnt-Like Protein-1 (BMAL1) Controls Circadian Cell Proliferation And Susceptibility To UVB-Induced DNA Damage In The Epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012
    2. New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence Journal of Investigative Dermatology · 2012
    3. The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity Nature · 2011
    4. Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
    5. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    6. Murine Vibrissae Cultured in Serum-Free Medium Reinitiate Anagen Journal of Investigative Dermatology · 2007
    7. Bone Morphogenetic Protein Signaling Regulates the Size of Hair Follicles and Modulates the Expression of Cell Cycle-Associated Genes Proceedings of the National Academy of Sciences of the United States of America · 2006
    8. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    9. Rat Hair Follicle Growth In Vitro British Journal of Dermatology · 1992