The Circadian Clock in Skin
January 2015
in “
Journal of Biological Rhythms
”
circadian clock skin biology stem cell functions tissue regeneration hair follicle regeneration cell proliferation DNA repair UV radiation DNA damage skin cancer immune functions psoriasis skin pigmentation UV protection Bmal1 cell cycle regulation UVB-induced DNA damage metabolic genes immune cell functions circadian disruption chronotherapy circadian rhythm skin health stem cells hair growth cell growth sun exposure immune system skin color sun protection Bmal1 gene cell cycle UVB damage metabolism genes immune cells time-based therapy
Studysummary This review discusses the role of the circadian clock in skin functions such as cell proliferation and UV protection and reports no new results; the authors note its potential in studying immune regulation and seasonal behaviors.
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