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GlossaryBMAL1

regulates circadian rhythms and influences biological processes like sleep

BMAL1, also known as Brain and Muscle ARNT-Like 1, is a crucial protein that plays a significant role in regulating the body's circadian rhythms, which are the natural cycles of physical, mental, and behavioral changes that follow a 24-hour cycle. It forms a complex with another protein called CLOCK, and together they help control the expression of genes that influence various biological processes, including sleep-wake cycles, metabolism, and even hair growth.

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research Timing of Expression of the Core Clock Gene Bmal1 Influences Its Effects on Aging and Survival

237 citations, February 2016 in “Science Translational Medicine”

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.