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    Glossary BMAL1

    regulates circadian rhythms and influences biological processes like sleep

    BMAL1, also known as Brain and Muscle ARNT-Like 1, is a crucial protein that plays a significant role in regulating the body's circadian rhythms, which are the natural cycles of physical, mental, and behavioral changes that follow a 24-hour cycle. It forms a complex with another protein called CLOCK, and together they help control the expression of genes that influence various biological processes, including sleep-wake cycles, metabolism, and even hair growth.

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    Research 30 of 114

    1. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012 · 221 citations
    2. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013 · 92 citations
    3. PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells Stem cell reports · 2017 · 22 citations
    4. The clock gene brain and muscle Arnt-like protein-1 (BMAL1) is involved in hair growth Archives of Dermatological Research · 2013 · 9 citations
    5. The circadian molecular clock creates epidermal stem cell heterogeneity Nature · 2011 · 293 citations
    6. Timing of expression of the core clock gene <i>Bmal1</i> influences its effects on aging and survival Science Translational Medicine · 2016 · 237 citations
    7. The Circadian Clock in Skin Journal of Biological Rhythms · 2015 · 127 citations
    8. Circadian clocks: from stem cells to tissue homeostasis and regeneration EMBO Reports · 2017 · 84 citations
    9. The Peripheral Clock Regulates Human Pigmentation 2014 · 81 citations
    10. Clock genes, hair growth and aging Aging · 2010 · 55 citations
    11. Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells Biochemical and biophysical research communications · 2012 · 38 citations
    12. Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle PLoS ONE · 2015 · 30 citations
    13. When the Circadian Clock Meets the Melanin Pigmentary System Journal of Investigative Dermatology · 2015 · 18 citations
    14. The clock within Nature · 2011 · 6 citations
    15. Overview of the Circadian Clock in the Hair Follicle Cycle Biomolecules · 2023
    16. Hair, Cutaneous Homeostasis and Stem Cell Functions Journal of Investigative Dermatology · 2014
    17. A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015 · 212 citations
    18. Function and underlying mechanisms of seasonal colour moulting in mammals and birds: what keeps them changing in a warming world? 2018 · 113 citations
    19. Neuroendocrinology of the hair follicle: principles and clinical perspectives Trends in Molecular Medicine · 2014 · 98 citations
    20. Olfactory receptor OR2AT4 regulates human hair growth Nature Communications · 2018 · 82 citations
    21. The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015 · 66 citations
    22. The cycling hair follicle as an ideal systems biology research model Experimental Dermatology · 2010 · 66 citations
    23. Mechanism of Sleep Disturbance in Children with Atopic Dermatitis and the Role of the Circadian Rhythm and Melatonin International Journal of Molecular Sciences · 2016 · 63 citations
    24. Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor BMC Endocrine Disorders · 2014 · 62 citations
    25. Module-based complexity formation: periodic patterning in feathers and hairs Wiley Interdisciplinary Reviews-Developmental Biology · 2012 · 47 citations
    26. Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture PLOS Biology · 2018 · 42 citations
    27. Aging in hair follicle stem cells and niche microenvironment The Journal of Dermatology · 2017 · 38 citations
    28. A primer for studying cell cycle dynamics of the human hair follicle Experimental Dermatology · 2016 · 38 citations
    29. Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix European Journal of Cell Biology · 2017 · 30 citations
    30. Hair Coloration by Gene Regulation: Fact or Fiction? Trends in biotechnology · 2015 · 15 citations