When The Circadian Clock Meets The Melanin Pigmentary System

    March 2015 in “ Journal of Investigative Dermatology ”
    Andrzej Słomiński, Rüdiger Hardeland, Rüssel J. Reiter
    Studysummary In this study, silencing BMAL1 and PER1 genes increased melanogenic activity in follicular and epidermal melanocytes, suggesting that peripheral circadian clocks may regulate melanin pigmentation.
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    Research cited in this study 5

    1. The Peripheral Clock Regulates Human Pigmentation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2014
    2. Local Circadian Clock Gates Cell Cycle Progression of Transient Amplifying Cells During Regenerative Hair Cycling Proceedings of the National Academy of Sciences of the United States of America · 2013
    3. Melatonin in the Skin: Synthesis, Metabolism, and Functions Trends in Endocrinology and Metabolism · 2008
    4. Melanogenesis Is Coupled to Murine Anagen: New Concepts for the Role of Melanocytes and Regulation of Melanogenesis in Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    5. Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993