Cosmeceutical Therapy: Addressing the Effects of UVR Photoaging on the Skin’s Circadian Rhythm

The review "Cosmeceutical Therapy: Engaging the Repercussions of UVR Photoaging on the Skin’s Circadian Rhythm" discusses the impact of Ultraviolet Radiation (UVR) on the skin's circadian rhythm and the potential of cosmeceuticals to mitigate these effects. Prolonged exposure to UVR can cause skin photodamage and disrupt the skin's circadian rhythm, leading to higher chances of DNA damage and potential skin cancer. The review suggests that understanding the skin's circadian rhythm could aid in developing better cosmeceutical products that not only suppress photoaging but remain effective throughout the day. It also highlights that humans are more sensitive to UVR-induced DNA damage during midday to late afternoon compared to morning exposure, suggesting that cosmetic products could be designed to maximize repair rates during the night and morning, while products containing sunscreen and antioxidant properties should be used in the afternoon when photodamage is at its peak. The document concludes that considering the skin's circadian rhythm in the manufacturing of cosmetic products could increase product efficacy and provide a form of precision therapy currently lacking in cosmetic science.