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Glossary Skin Damage

harm to skin's structure and function from various factors

Skin damage refers to any harm or injury to the skin's structure and function, which can result from various factors such as UV radiation, physical trauma, chemical exposure, or infections. This damage can manifest as sunburn, cuts, abrasions, rashes, or more severe conditions like burns and chronic wounds, potentially leading to complications like scarring, infection, or impaired healing.

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Research

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research Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage

20 citations , February 2017 in “International Journal of Dermatology”

This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.

research Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage

15 citations , November 2018 in “Current radiopharmaceuticals”

This study found that melatonin, when administered to Wistar rats prior to and after radiation exposure, reduced oxidative stress markers and histopathological damage in skin tissue compared to radiation alone, suggesting it may effectively prevent and treat radiation-induced skin injury.

Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway

research Clionasterol-Rich Fraction of Caulerpa racemosa against Particulate Matter-Induced Skin Damage via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway

5 citations , September 2022 in “Antioxidants”

This study found that the clionasterol-rich hexane fraction of Caulerpa racemosa may protect against particulate matter-induced skin damage by reducing oxidative stress and mitochondrial-mediated apoptosis in human keratinocytes and zebrafish.

research Porcine skin damage thresholds and histological damage characteristics from 1319-nm laser radiation

5 citations , September 2019 in “Journal of Biomedical Optics”

This study determined in-vivo skin damage thresholds for 1319-nm laser exposure in pigs, and the findings may enhance understanding of thermal damage mechanisms and inform laser safety standards.

research Keratin 17 Impacts Global Gene Expression and Controls G2/M Cell Cycle Transition in Ionizing Radiation–Induced Skin Damage

3 citations , July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, researchers found that K17−/− mice suffered more severe hair follicle damage but showed reduced epidermal inflammation after ionizing radiation, with K17's absence leading to aberrant cell cycle progression due to altered p53 genome binding and reduced B-Myb degradation.

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Community Join

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community (/r/science X-post): Stress may turn your hair grey. The appearance of grey hairs after periods of stress or skin damage could be the result of depletion of stem cells from the base of the hair follicle, according to a new study : science

4 upvotes 13 years ago

Stress can cause hair to turn grey due to stem cell depletion at the hair follicle base. Treatments discussed include Minoxidil, finasteride, and RU58841 for hair loss.

community Does microneedling damage scalp?

in Research/Science 12 upvotes 2 years ago

Microneedling does not prevent future hair transplants, but some surgeons report the skin becomes "harder" in treated areas. There is no clear evidence to confirm this effect.

community microneedle, any long term users damage?

in Microneedling 35 upvotes 2 years ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community Are these derma rollers bad/ineffective? Bought this just a few days ago and today I was watching a YT video where the guy said that these stainless steel ones can be more harmful and that the ones with titanium needles should be preferred. So should I buy a titanium one or am I okay with these?

in Product 12 upvotes 1 month ago

Titanium-tipped derma stamps are preferred over stainless steel rollers for safer and more effective skin treatment. Rollers can cause skin damage if used incorrectly, while stamps provide cleaner punctures.

community How to take care of the microneedler?

in Microneedling 7 upvotes 1 year ago

Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skin damage, so stamps or pens are recommended for safer microneedling.

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Learn

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learn Tretinoin

the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

learn Epidermal Growth Factor

learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Sulforaphane

compound from cruciferous vegetables has some mild effects on DHT

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Clinics

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Experts

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35
SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin