Protective Role of Melatonin and Its Metabolites in Skin Aging

    January 2022 in “ International Journal of Molecular Sciences ”
    Georgeta Bocheva, Radomir M. Slominski, Zorica Janjetovic … Andrzej Slominski
    Studysummary This review discusses the impact of melatonin and its metabolites on skin aging, summarizing how they may serve as "aging neutralizers" through their anti-oxidative and anti-inflammatory properties, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 20

    1. Clinical and Biological Impact of the Exposome on the Skin Journal of the European Academy of Dermatology and Venereology · 2020
    2. New Aspects of Vitamin D Metabolism and Action: Addressing the Skin as Source and Target Nature Reviews Endocrinology · 2020
    3. Protective Effects of Melatonin on the Skin: Future Perspectives International Journal of Molecular Sciences · 2019
    4. The Dynamics of the Skin’s Immune System International Journal of Molecular Sciences · 2019
    5. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018
    6. Clinical Cosmeceutical Repurposing of Melatonin in Androgenic Alopecia Using Nanostructured Lipid Carriers Prepared with Antioxidant Oils Expert Opinion on Drug Delivery · 2018
    7. Reversing Wrinkled Skin and Hair Loss in Mice by Restoring Mitochondrial Function Cell death and disease · 2018
    8. Melatonin: A Cutaneous Perspective on Its Production, Metabolism, and Functions Journal of Investigative Dermatology · 2018
    9. Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition Journal of Investigative Dermatology · 2016
    10. Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions Molecular and Cellular Endocrinology · 2012
    11. Differential Effects of Melatonin as a Broad Range UV-Damage Preventive Dermato-Endocrine Regulator Dermato-endocrinology · 2011
    12. Melatonin as a Major Skin Protectant: From Free Radical Scavenging to DNA Damage Repair Experimental dermatology · 2008
    13. Melatonin in the Skin: Synthesis, Metabolism, and Functions Trends in Endocrinology and Metabolism · 2008
    14. Melatonin and the Hair Follicle Journal of pineal research · 2007
    15. The Role of Melatonin in Neuroectodermal-Mesodermal Interactions: The Hair Follicle Synthesizes Melatonin and Expresses Functional Melatonin Receptors ˜The œFASEB journal · 2005
    16. The Cutaneous Serotoninergic/Melatoninergic System: Securing a Place Under the Sun ˜The œFASEB journal · 2005
    17. On the Role of Melatonin in Skin Physiology and Pathology Endocrine journal · 2005
    18. Melatonin Increases Anagen Hair Rate in Women With Androgenetic Alopecia or Diffuse Alopecia: Results of a Pilot Randomized Controlled Trial British Journal of Dermatology · 2004
    19. Characterization of the Serotoninergic System in the C57BL/6 Mouse Skin European journal of biochemistry · 2003
    20. Serotoninergic And Melatoninergic Systems Are Fully Expressed In Human Skin ˜The œFASEB journal · 2002

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    1. Protective Role of Melatonin and Its Metabolites in Skin Aging International Journal of Molecular Sciences · 2022