Melatonin as a Major Skin Protectant: From Free Radical Scavenging to DNA Damage Repair

July 2008 in “ Experimental dermatology ”

Tobias W. Fischer, Andrƶej Slominski, Michał A. Żmijewski, Rüssel J. Reiter, Ralf Paus

melatonin free radical scavenging DNA damage repair antioxidant oxidative stress skin cells DNA repair mechanisms skin integrity environmental skin aging intrinsic skin aging

TLDR Melatonin protects the skin by scavenging free radicals and repairing DNA damage.

The document discussed the role of melatonin as a significant skin protectant, highlighting its functions from free radical scavenging to DNA damage repair. It emphasized melatonin's antioxidant properties, which helped neutralize harmful free radicals, thereby protecting skin cells from oxidative stress. Additionally, melatonin was shown to enhance DNA repair mechanisms, contributing to the maintenance of skin integrity and prevention of damage. The study underscored the potential therapeutic applications of melatonin in dermatology, particularly in protecting against environmental and intrinsic skin aging factors.

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