Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen

    Kerstin Foitzik, Karoline Krause, A. J. Nixon … Ralf Paus
    Studysummary This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.
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    Research cited in this study 12

    1. Hormonal Basis of Male and Female Androgenic Alopecia: Clinical Relevance Skin Pharmacology and Physiology · 2009
    2. Enzymology of the Hair Follicle PubMed · 2001
    3. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    4. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice Endocrinology · 2001
    5. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice Endocrinology · 2001
    6. Identification of Differentially Expressed Genes During a Wool Follicle Growth Cycle Induced by Prolactin Journal of Investigative Dermatology · 1999
    7. The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle Annals of the New York Academy of Sciences · 1999
    8. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    9. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    10. Growth of Secondary Hair Follicles of the Cashmere Goat In Vitro and Their Response to Prolactin and Melatonin PubMed · 1994
    11. Does Prolactin Play a Role in Skin Biology and Pathology? Medical hypotheses · 1991
    12. Hormonal Diagnosis of So-Called Androgenetic Alopecia in Women Geburtshilfe und Frauenheilkunde · 1988

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    2. Molecular And Cellular Basis Of Exogen And Anagen Induction Durham e-Theses (Durham University) · 2007
    3. Hair Follicle Regeneration After Implantation of Hair Follicle Cells into Subcutis of Nude Mice PubMed · 2004
    4. Effects of Substance P on the Expression of Various Factors to Control Hair Growth in Human Hair Follicle Culture Linchuang pifuke zazhi · 2004