Hair Follicle Regeneration After Implantation of Hair Follicle Cells into Subcutis of Nude Mice
July 2004
in “
PubMed
”
hair follicle regeneration hair follicle cells subcutis nude mice human scalp hair papilla cells dermal sheath cells fibroblasts hair follicle epithelium cells hair follicle-like structures in vivo early passage cultured hair papilla cells hair regeneration hair cells skin layer lab mice scalp cells sheath cells skin cells epithelium cells hair structures live organism early cultured cells
TLDR Hair follicle-like structures can form when specific hair cells are mixed and implanted in mice.
The study aimed to observe hair follicle regeneration by implanting cultured hair follicle cells into the subcutis of nude mice. Researchers mixed human scalp hair papilla cells, dermal sheath cells, and fibroblasts with hair follicle epithelium cells in different ratios and implanted them into the mice. Results showed that hair follicle-like structures formed when hair papilla cells were mixed with hair follicle epithelium cells, but no hair follicles formed when the epithelium was mixed with dermal sheath cells or fibroblasts. The conclusion was that hair follicle-like structures could be generated in vivo when early passage cultured hair papilla cells were mixed with hair follicle epithelium cells and implanted into the subcutis of nude mice.
