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research Industrial-scale processing of activated platelet-rich plasma from specific pathogen-free pigs and its effect on promoting human hair follicle dermal papilla cell cultivation

7 citations , December 2016 in “Journal of The Taiwan Institute of Chemical Engineers”

This study found that porcine platelet-rich plasma can be a commercially viable replacement for fetal bovine serum with similar effectiveness in promoting human hair follicle cell growth.

research Industrial-scale processing of activated platelet-rich plasma from specific pathogen-free pigs and its effect on promoting human hair follicle dermal papilla cell cultivation

February 2017 in “Spectrum Research Repository (Concordia University)”

This study confirmed porcine PRP's commercial viability as a fetal bovine serum replacement, showing higher growth factor levels and stability, without increasing human follicle dermal papilla cell proliferation compared to FBS.

research Anti-Hair Loss Activity of Healthy Human Scalp-Derived Staphylococcus capitis KMH304 Ferment Filtrate in Human Hair-Follicle Dermal Papilla and Keratinocyte Cells

April 2026 in “Microorganisms”

This study suggests that Staphylococcus capitis ferment filtrate (SCFF) may promote hair growth and scalp health by modulating pathways related to hair loss, aging, and oxidative stress in vitro.

research Cultured dermal papilla cells from androgen-dependent human hair follicles (e.g. beard) contain more androgen receptors than those from non-balding areas of scalp

124 citations , April 1992 in “Journal of Endocrinology/Journal of endocrinology”

This study observed that cells from androgen-sensitive areas like the beard and scrotum showed higher androgen receptor levels compared to those from non-balding scalp areas, supporting the role of dermal papilla in follicle growth responses to androgens.

research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells

8 citations , November 2020 in “Frontiers in Cell and Developmental Biology”

This study reported that exogenous R-spondin-1 can restore hair follicle neogenesis in adult mouse cells, highlighting differences in gene expression and signaling pathways between fetal and adult dermal papilla cells.

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Community Join

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community Hair cloning breakthrough, this might just be the big one ?

418 upvotes 6 months ago

Japanese scientists discovered ABM cells, enabling successful human hair follicle cloning, potentially curing hair loss. The treatment may be available in Japan by 2028, but it will be expensive and require travel.

community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

7 upvotes 5 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Hair Multiplication Projects in China - Promising clinical trial results on Mice

34 upvotes 1 year ago

A breakthrough in hair follicle cultivation using induced pluripotent stem cells (iPSCs) has been achieved, producing large hair follicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.

community The Real Reason For Hair Loss?

9 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

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Learn

9 / 34 results

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Stem Cell Factor

learn SCUBE3

Signalling protein made in the hair follicle

learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

learn Exosomes

Tiny cell-derived particles offered by clinics as an injectable treatment

learn Vitamin C

Is topical Vitamin C effective for scalp and hair growth? No human trial has shown that topical vitamin C improves hair growth or scalp health. Its skin trials were on other body sites, and the hair data come from laboratory studies.

learn Vitis vinifera

Can grape extract help with scalp circulation or hair growth? There is no human evidence that grape extract improves scalp blood flow or hair growth; the related data are on blood pressure and in mice.

learn Ginkgo biloba

Does ginkgo biloba improve scalp circulation, and does that help hair regrowth? No human study has shown that ginkgo improves scalp circulation or regrows hair; the direct hair evidence is a 1993 mouse study. Ginkgo may increase bleeding risk, especially with blood thinners.
Can ginkgo biloba reduce scalp inflammation that contributes to hair loss? There is no human evidence that ginkgo reduces scalp inflammation or helps hair loss. Ginkgo may increase bleeding risk and interact with medicines, so talk to a doctor or pharmacist first.

learn sh-Polypeptide-7

Does sh-Polypeptide-7 stimulate hair follicles or reduce scalp inflammation? sh-Polypeptide-7 is the INCI name for a lab-made form of human growth hormone (somatotropin) — not EGF, which is sh-Oligopeptide-1. Growth hormone and IGF-1 signalling is documented in hair follicle biology, but there is no published human trial of sh-Polypeptide-7 applied to the scalp for hair growth or scalp inflammation.

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Clinics

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All 12 clinic results →

Experts

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Trichologist
Kirsten J. Scalp
Greenville, SC, United States

Kirsten J. Scalp