Industrial-Scale Processing of Activated Platelet-Rich Plasma from Specific Pathogen-Free Pigs and Its Effect on Promoting Human Hair Follicle Dermal Papilla Cell Cultivation

    February 2017 in “ Spectrum Research Repository (Concordia University) ”
    Joyce Chen, Lin, YK (Lin, Yung-Kai), Sugiri, F (Sugiri, Fendi), Ma, H (Ma, Hsu), Chiu, YH (Chiu, Yen-Hao), Yao, CL (Yao, Chao-Ling)
    TLDR Porcine PRP can replace FBS and promote hair growth.
    This study aimed to optimize the production of porcine platelet-rich plasma (PRP) as a potential replacement for fetal bovine serum (FBS) and to evaluate its effects on human hair follicle dermal papilla cells (HFDPCs). The researchers developed a protocol for large-scale production of porcine PRP, which was activated using collagen, thrombin, and calcium chloride. The study found that porcine PRP had higher growth factor levels than FBS and remained stable during freeze-drying and surfactant treatments. However, HFDPCs treated with porcine PRP showed no significant difference in proliferation compared to those treated with FBS. The study concluded that porcine PRP could be a commercially viable alternative to FBS and a promoter of hair growth.
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      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  6 upvotes 1 year ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 3 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 2 years ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  12 upvotes 2 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

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