PP405 - hair stem cell stimulation
    Research/Science 3/9/2024

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    In this educational post, the primary subjects mentioned are
    💧 PP405 (topical)
    the tone is 😐 neutral.

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    PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
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      community Possible natural pp405 solution

      in Research/Science  45 upvotes 1 month ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 1 month ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

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