PP405 - hair stem cell stimulation
    Research/Science 3/9/2024

    At a glance
    In this educational post, the primary subjects mentioned are
    💧 PP405 (topical)
    the tone is 😐 neutral.

    Other terms

    PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
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      community The mechanism of androgenic alopecia

      in Research/Science  32 upvotes 2 weeks ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 1 month ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  210 upvotes 3 days ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

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