PP405 - hair stem cell stimulation
    Research/Science 3/9/2024

    At a glance
    In this educational post, the primary subjects mentioned are
    💧 PP405 (topical)
    the tone is 😐 neutral.

    Other terms

    PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
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    5 / 159 results

      community Possible natural pp405 solution

      in Research/Science  42 upvotes 1 week ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 2 weeks ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community PP405 bandwagon, time to resume the hype train.

      in Treatment  151 upvotes 2 days ago
      PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

      community Why so much hate for PP405 all of a sudden?

      in Technology  43 upvotes 2 weeks ago
      PP405 is a new hair loss treatment facing mixed reactions due to initial hype and insufficient data. Some are hopeful, but many doubt its effectiveness compared to minoxidil and finasteride.

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