PP405 - hair stem cell stimulation Research/Science 3/9/2024
PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
View this post in the Community →
Similar Community Posts Join
5 / 241 resultscommunity I think we should all keep an eye out for Pelage PP405. February 2025 will be interesting.
Pelage PP405 is a new hair loss treatment in trials, potentially reactivating dormant hair follicles without affecting hormones. Results are expected in February 2025, offering an alternative to minoxidil and finasteride.
community Anybody else obsessively searching for pp405 and counting the days?
People are eagerly awaiting the release of PP405, a new hair loss treatment. Some are using minoxidil and finasteride in the meantime, but there are concerns about scams and unverified products.
community Possible natural pp405 solution
Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

community PP405 Identity Research
PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.
community Anyone heard of scube3? And other emerging treatments?
Emerging hair loss treatments like PP405, a topical MPC inhibitor, show promise in activating stem cells for hair growth. The conversation seeks information on the development stages and accessibility of these treatments.
Related Research
6 / 18 results
research Review of the 2024 American Academy of Dermatology Annual Meeting
New treatments for skin conditions show promise, especially Coacillium® for hair growth in young people with alopecia areata.

research Recent Advances in Drug Development for Hair Loss
New treatments for hair loss show promise with advanced therapies and better targeting.

research Complementary and Alternative Medicine for Vitiligo
Eat antioxidant-rich foods, reduce fast food, and explore various treatments for vitiligo.

research Eosinophilic Folliculitis in a Dog
A dog with skin issues improved with prednisone after accurate diagnosis.

research Trichoscopy: Usefulness in Diagnosing Hair Loss in Adult Female Patients
Trichoscopy is a helpful and quick method to identify different types of hair loss in women.