Platelet-Rich Plasma Promotes Cell Viability of Human Hair Dermal Papilla Cells In Vitro

    January 2017 in “ PubMed ”
    Yuyan Wang, Chunmiao Zheng, Fei Zhu, Ming Jia
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    Studysummary This study found that platelet-rich plasma significantly enhanced the viability, as well as the expression of alkaline phosphatase and versican, in human hair dermal papilla cells compared to controls. Our plain-language summary of this paper — not a Tressless recommendation.
    The study demonstrated that platelet-rich plasma (PRP) significantly promoted the viability and proliferation of human hair dermal papilla cells (HHDPCs) in vitro, particularly at a 5% concentration. PRP also increased the expression of alkaline phosphatase (ALP) and versican at both mRNA and protein levels. The study involved 8 healthy volunteers and used MTT assays, qRT-PCR, and Western blot analysis. These findings suggested that PRP could be a potential therapeutic tool for promoting hair follicle regeneration and treating alopecia, although further research is needed to identify the specific growth factors responsible for these effects.
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