In this study, human umbilical cord mesenchymal stem cell-derived exosomes were found to promote the growth of human hair dermal papilla cells, partly by enhancing AKT-dependent signaling pathways, suggesting a potential role in treating hair loss.
This study found that platelet-rich plasma significantly enhanced the viability, as well as the expression of alkaline phosphatase and versican, in human hair dermal papilla cells compared to controls.
September 2026 in “Journal of Biophotonics” This study indicates that microwave-assisted Opuntia humifusa extract combined with Red-LED irradiation may better modulate intracellular redox status and Wnt/β-catenin-related protein expression in human hair follicle dermal papilla cells than each treatment alone.
April 2024 in “Cellular signalling” This study on mice found that activating TRPML channels with MLSA1 promoted hair regeneration, accelerated hair cycle transition, and influenced human dermal papilla cells to secrete hair growth promoting factors while reducing hair growth inhibitors and oxidative damage.
November 2018 in “Journal of investigative dermatology, venereology and cosmetology” This study found that Biofield Energy Healing significantly increased the proliferation of human hair follicle dermal papilla cells in vitro, suggesting it may promote hair growth.