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    Glossary Alkaline Phosphatase

    enzyme that breaks down proteins in various body tissues

    Alkaline Phosphatase (ALP) is an enzyme found in various tissues throughout the body, including the liver, bones, kidneys, and digestive system. It plays a crucial role in breaking down proteins and is often measured in blood tests to help diagnose liver disease, bone disorders, and other conditions. Elevated or decreased levels of ALP can indicate issues such as liver damage, bone growth abnormalities, or bile duct obstructions.

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    1. Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells PLOS ONE · 2012 · 85 citations
    2. Alkaline Phosphatase in Alopecia Areata Archives of Dermatology · 1957 · 23 citations
    3. Overexpression of alkaline phosphatase improves the hair-inductive capacity of cultured human dermal papilla spheres Journal of Dermatological Science · 2019 · 13 citations
    4. Effects of the anti-androgen finasteride on 5α-reduction of androgens in the presence of progesterone in human gingival fibroblasts: modulatory actions of the alkaline phosphatase inhibitor levamisole Journal of Periodontal Research · 2000 · 9 citations
    5. Proteomics demonstration that histone H4 is a colchicine-induced retro-modulator of growth and alkaline phosphatase activity in hair follicle dermal papilla culture Journal of proteomics · 2011 · 5 citations
    6. Distribution of acid and alkaline phosphatases in canine skin. PubMed · 1975 · 3 citations
    7. Tetrathiomolybdate Decreases the Expression of Alkaline Phosphatase in Dermal Papilla Cells by Increasing Mitochondrial ROS Production International journal of molecular sciences · 2023 · 2 citations
    8. Alkaline Phosphatase Reaction in Hair Follicles of Male Beagle Dogs during Hair Cycle Stages* Anatomia Histologia Embryologia · 1978 · 2 citations
    9. SAT-724 Persistently Elevated Alkaline Phosphatase in an Older Woman with a History of Breast Cancer Journal of the Endocrine Society · 2025
    10. 705 Ablation of alkaline phosphatase in human dermal papilla spheroid impairs hair follicle induction Journal of Investigative Dermatology · 2016
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    1. KY19382 Experimental compound that activates hair-growth signals, tested only in animals

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