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    Glossary Bone Metabolism

    continuous process of bone breakdown and rebuilding

    Bone metabolism refers to the continuous process by which bones are broken down (resorption) and rebuilt (formation). This dynamic process involves the coordinated activity of osteoclasts, which break down bone tissue, and osteoblasts, which form new bone. Proper bone metabolism is crucial for maintaining bone strength and density, and imbalances can lead to conditions such as osteoporosis.

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      Gonadal Dysgenesis and Bone Metabolism

      research Gonadal dysgenesis and bone metabolism

      45 citations , February 2001 in “Joint bone spine”
      This study found that Turner’s syndrome is associated with significant bone mass decrease due to estrogen deficiency, which can be improved with estrogen therapy, while bone issues in Klinefelter’s syndrome may benefit from early androgen therapy and possibly bisphosphonates.

      research RANKL biology: bone metabolism, the immune system, and beyond

      519 citations , February 2020 in “Inflammation and Regeneration”
      This review discusses the diverse roles of the RANKL/RANK/OPG system in bone metabolism, the immune system, and other biological processes, emphasizing its relevance in the field of osteoimmunology, but reports no new results.
      The Role of R-Spondins and Their Receptors in Bone Metabolism

      research The role of R-spondins and their receptors in bone metabolism

      25 citations , May 2016 in “Progress in Biophysics & Molecular Biology”
      This article reviews the role of R-spondins and their receptors in bone development and metabolism, highlighting their potential modulatory effects and clinical implications for treating bone loss diseases, but reports no new clinical results.

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      community What happens if you combine dutasteride and a aromataze inhibitor?

       4 upvotes 7 years ago
      Combining dutasteride and an aromatase inhibitor may increase testosterone levels significantly, potentially enhancing athletic performance but also posing health risks like elevated blood pressure and worsened cholesterol. The user is experimenting with dutasteride, anastrozole, minoxidil, and ketoconazole shampoo to manage hair loss and estradiol levels, while monitoring side effects and hormone levels.

      community PP405 mechanism question - looking for discussion

       7 upvotes 5 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Does DHT give you a leaner face?

      in Finasteride/Dutasteride  44 upvotes 1 year ago
      Finasteride and dutasteride may increase estrogen levels, leading to water retention and a fuller face. Users discuss managing these effects with lifestyle changes and supplements like zinc and DIM.

      community Blaming Finasteride doesn't help you solve anything: dry eyes

       51 upvotes 1 year ago
      Finasteride is debated for causing dry eyes, with some users experiencing relief after stopping it, while others find no connection. Topical treatments like dutasteride and minoxidil are suggested as alternatives, with advice to consult medical professionals.

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      learn Vitamin D

      vitamin you should probably be taking for general health might also help your hair a little

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss