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    Glossary CYP27B1

    enzyme converting inactive vitamin D to its active form

    CYP27B1, also known as 25-hydroxyvitamin D3 1-alpha-hydroxylase, is an enzyme that plays a crucial role in the metabolism of vitamin D. It converts inactive vitamin D into its active form, calcitriol, which is essential for calcium absorption and bone health. This enzyme is important for maintaining proper levels of calcium and phosphate in the blood, which are vital for normal bone formation and maintenance.

    Research 10 of 160

    1. Nongenomic effects of 1α,25-dihydroxyvitamin D 3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice Biochemical and biophysical research communications · 2017 · 11 citations
    2. A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid 1998 · 58 citations
    3. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice Endocrine reviews · 2008 · 1533 citations
    4. Genetic Disorders and Defects in Vitamin D Action Endocrinology and metabolism clinics of North America · 2010 · 151 citations
    5. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations
    6. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    7. The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3 The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 37 citations
    8. Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways British Journal of Dermatology · 2017 · 27 citations
    9. Ligand‐Independent Actions of the Vitamin D Receptor: More Questions Than Answers JBMR plus · 2021 · 11 citations
    10. The Endocrine Function of the Skin: An Analytical Narrative Apollo medicine · 2023
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