Search
for

    Glossary CYP27B1

    enzyme converting inactive vitamin D to its active form

    CYP27B1, also known as 25-hydroxyvitamin D3 1-alpha-hydroxylase, is an enzyme that plays a crucial role in the metabolism of vitamin D. It converts inactive vitamin D into its active form, calcitriol, which is essential for calcium absorption and bone health. This enzyme is important for maintaining proper levels of calcium and phosphate in the blood, which are vital for normal bone formation and maintenance.

    Sort by

    Research 30 of 159

    1. Nongenomic effects of 1α,25-dihydroxyvitamin D 3 on cartilage formation deduced from comparisons between Cyp27b1 and Vdr knockout mice Biochemical and biophysical research communications · 2017 · 11 citations
    2. A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid 1998 · 58 citations
    3. Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice Endocrine reviews · 2008 · 1533 citations
    4. Genetic Disorders and Defects in Vitamin D Action Endocrinology and metabolism clinics of North America · 2010 · 151 citations
    5. Extraskeletal actions of vitamin D Annals of the New York Academy of Sciences · 2016 · 119 citations
    6. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    7. The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3 The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 37 citations
    8. Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways British Journal of Dermatology · 2017 · 27 citations
    9. Ligand‐Independent Actions of the Vitamin D Receptor: More Questions Than Answers JBMR plus · 2021 · 11 citations
    10. The Endocrine Function of the Skin: An Analytical Narrative Apollo medicine · 2023
    11. PSAT217 Estrogen Deficiency as a Cause of Decreased 1- alpha - hydroxylase Activity Journal of the Endocrine Society · 2022
    12. BJD Snippet Journal of Cosmetic Dermatology · 2017
    13. The Role of Vitamin D and Its Receptor in Hair Follicle Biology Elsevier eBooks · 2017
    14. Generation of Genetically Modified Rats Using CRISPR/Cas9 Genome-Editing System to Reveal Novel Vitamin D Actions Medical Research Archives · 2021
    15. Cutaneous Retinoic Acid Levels Determine Hair Follicle Development and Downgrowth 2012 · 31 citations
    16. Vitamin A Metabolism During Refractory Telogen Current developments in nutrition · 2020
    17. Editorial: Vitamin D 1α-Hydroxylase Knockout Mice as a Hereditary Rickets Animal Model Endocrinology · 2001 · 7 citations
    18. Vitamin D metabolism and function in the skin Molecular and cellular endocrinology · 2011 · 185 citations
    19. ラット精巣におけるビタミンD 代謝関連遺伝子の発現解析 Institutional Repositories DataBase (IRDB) · 2025
    20. Skin steroidogenesis in health and disease Reviews in endocrine and metabolic disorders · 2016 · 47 citations
    21. The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia Skin Pharmacology and Physiology · 2015 · 15 citations
    22. Genetic variations associated with response to dutasteride in the treatment of male subjects with androgenetic alopecia PLOS ONE · 2019 · 3 citations
    23. Vitamin D and the skin: Focus on a complex relationship: A review Journal of Advanced Research · 2014 · 139 citations
    24. Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases Pharmacological Reports · 2023 · 47 citations
    25. Chronic Stress Suppresses the Expression of Cutaneous Hypothalamic–Pituitary–Adrenocortical Axis Elements and Melanogenesis PLoS ONE · 2014 · 40 citations
    26. Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis Biomolecules · 2017 · 24 citations
    27. Dermatologic manifestations of endocrine disorders Current Opinion in Pediatrics · 2012 · 11 citations
    28. Gender difference in relationship between serum ferritin and 25-hydroxyvitamin D in Korean adults PLOS ONE · 2017 · 10 citations
    29. Role of skin enzymes in metabolism of topical drugs Metabolism and Target Organ Damage · 2024 · 6 citations
    30. Increased 25(OH)D3 level in redheaded people: Could redheadedness be an adaptation to temperate climate? Experimental dermatology · 2020 · 5 citations