Tetrathiomolybdate Decreases the Expression of Alkaline Phosphatase in Dermal Papilla Cells by Increasing Mitochondrial ROS Production

February 2023 in “ International journal of molecular sciences ”

Li Fan, Hongli Liu, Xiaojing Wu, Zhicheng Song, Haojia Tang, Maohua Gong, Lei Liu, Fuchang Li

tetrathiomolybdate Alkaline Phosphatase Dermal Papilla Cells mitochondrial ROS ATP production copper supplementation hair growth Reactive Oxygen Species DPC function TM ALP DPCs ROS

Studysummary This study identified that copper depletion in dermal papilla cells reduced hair growth by boosting ROS levels, but ROS scavengers like NAC and ascorbic acid partially alleviated this effect.

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