Industrial-Scale Processing of Activated Platelet-Rich Plasma from Specific Pathogen-Free Pigs and Its Effect on Promoting Human Hair Follicle Dermal Papilla Cell Cultivation

December 2016 in “ Journal of The Taiwan Institute of Chemical Engineers ”

Yung-Kai Lin, Fendi Sugiri, Hsu Ma, Yen-Hao Chiu, Chao-Ling Yao

platelet-rich plasma porcine PRP human follicle dermal papilla cells HFDPCs collagen thrombin calcium chloride growth factors fetal bovine serum FBS hair growth cycle freeze-drying surfactant treatments PRP human dermal papilla cells bovine serum hair growth

From the encyclopedia

Platelet-Rich Plasma →

growth factors taken from your blood and injected into your scalp to stimulate hair

collagen →

Studysummary This study found that porcine platelet-rich plasma can be a commercially viable replacement for fetal bovine serum with similar effectiveness in promoting human hair follicle cell growth. Our plain-language summary of this paper — not a Tressless recommendation.

In 2017, a study was conducted to optimize the production of porcine platelet-rich plasma (PRP) and assess its effects on human follicle dermal papilla cells (HFDPCs), which are crucial for the hair growth cycle. The researchers developed a large-scale production process for porcine PRP, which was activated using a combination of collagen, thrombin, and calcium chloride. The study found that porcine PRP had higher growth factor levels than fetal bovine serum (FBS), a commonly used serum additive, and was stable during freeze-drying and surfactant treatments. HFDPCs treated with freshly prepared or freeze-dried PRP showed no significant difference in proliferation compared to FBS. The study concluded that porcine PRP is commercially viable as an FBS replacement and hair growth promoter.

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