Industrial-Scale Processing of Activated Platelet-Rich Plasma from Specific Pathogen-Free Pigs and Its Effect on Promoting Human Hair Follicle Dermal Papilla Cell Cultivation

    Yung-Kai Lin, Fendi Sugiri, Hsu Ma, Yen-Hao Chiu, Chao-Ling Yao
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    TLDR Pig blood plasma can be used to promote human hair growth and is a good alternative to the commonly used serum additive.
    In 2017, a study was conducted to optimize the production of porcine platelet-rich plasma (PRP) and assess its effects on human follicle dermal papilla cells (HFDPCs), which are crucial for the hair growth cycle. The researchers developed a large-scale production process for porcine PRP, which was activated using a combination of collagen, thrombin, and calcium chloride. The study found that porcine PRP had higher growth factor levels than fetal bovine serum (FBS), a commonly used serum additive, and was stable during freeze-drying and surfactant treatments. HFDPCs treated with freshly prepared or freeze-dried PRP showed no significant difference in proliferation compared to FBS. The study concluded that porcine PRP is commercially viable as an FBS replacement and hair growth promoter.
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      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 3 weeks ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community Platelet rich plasma treatment

      in Treatment  6 upvotes 7 months ago
      A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

      community platelet rich plasma experiences/thoughts?

      in Treatment  3 upvotes 2 years ago
      Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Platelet rich plasma treatment is considered expensive but cheaper than hair transplant.

      community PRP ( PLATELET-RICH-PlASMA) for hair loss

      in Treatment  1 upvotes 1 year ago
      A 27-year-old male experiencing hair loss post-Covid is considering PRP (platelet-rich plasma) therapy. He's seeking personal experiences about the process, particularly regarding pain levels, despite his dermatologist's assurance of using local anesthesia.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  14 upvotes 1 year ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

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