Finasteride Cream in Hirsutism

January 2001 in “ Endocrine Practice ”

K. Jean Lucas

finasteride hirsutism hair growth hormone levels Propecia

TLDR Finasteride cream reduces hair growth in women with hirsutism, but more research needed.

The study examined the effectiveness of finasteride cream in treating hirsutism in women. The cream was found to reduce hair growth in women with hirsutism and had few side effects. Finasteride cream could be a promising treatment option for hirsutism. The study suggests that finasteride cream may be a useful therapy for mild facial hirsutism in women with various causes and hormone levels. However, more research is needed to fully understand its long-term effects and optimal use.

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Research cited in this study

16 / 16 results

research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism

75 citations, October 1999 in “European journal of endocrinology”

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

research Comparison of Finasteride and Flutamide in the Treatment of Idiopathic Hirsutism

32 citations, July 1999 in “Fertility and Sterility”

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

research Effect of Finasteride in Idiopathic Hirsutism

27 citations, November 1998 in “Journal of Endocrinological Investigation”

Finasteride significantly reduces hair growth in women with idiopathic hirsutism.

research Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism

76 citations, December 1997 in “Fertility and Sterility”

Finasteride reduces hair growth better, but spironolactone has more side effects.

Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

75 citations, November 1996 in “Fertility and Sterility”

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives

50 citations, July 1996 in “Fertility and Sterility”

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

research A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women

52 citations, January 1995 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

research Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism

33 citations, October 1994 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride reduces hair growth and is safe for women with excessive hair.

research Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women

22 citations, September 1994 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin

34 citations, February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1040 citations, October 1992 in “The New England Journal of Medicine”

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

research Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men

30 citations, August 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride doesn't affect hormone levels in normal men.

Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

34 citations, February 1992 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride and minoxidil together promote hair growth better than either alone.

research Treatment of Hirsutism with the Pure Antiandrogen Flutamide

130 citations, September 1990 in “Journal of the American Academy of Dermatology”

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

research Ketoconazole Therapy for Women with Acne and/or Hirsutism

46 citations, August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers

147 citations, April 1990 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride safely lowers DHT levels without affecting testosterone.

Related Research

14 / 14 results

research The Efficacy and Use of Finasteride in Women: A Systematic Review

23 citations, January 2019 in “International Journal of Dermatology”

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

research Insulin Sensitizers for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials

121 citations, April 2008 in “The Journal of Clinical Endocrinology & Metabolism”

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

research A randomized bilateral vehicle-controlled study of eflornithine cream combined with laser treatment versus laser treatment alone for facial hirsutism in women

125 citations, February 2007 in “Journal of the American Academy of Dermatology”

research Randomized, double‐blind clinical evaluation of the efficacy and safety of topical eflornithine HCl 13.9% cream in the treatment of women with facial hair

133 citations, July 2006 in “International Journal of Dermatology”

research Hirsutism

271 citations, December 2005 in “New England journal of medicine/The New England journal of medicine”

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

research Comparison of High-Dose Finasteride (5 mg/day) Versus Low-Dose Finasteride (2.5 mg/day) in the Treatment of Hirsutism

51 citations, October 2002 in “European journal of endocrinology”

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

research Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism

63 citations, March 2001 in “Fertility and Sterility”

Diane 35 plus finasteride is more effective for treating hirsutism.

research Lack of Effect of Topical Finasteride Suggests an Endocrine Role for Dihydrotestosterone

12 citations, August 2000 in “Fertility and Sterility”

Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.

research A Comparative Study of a Gonadotropin-Releasing Hormone Agonist and Finasteride on Idiopathic Hirsutism

10 citations, January 2000 in “PubMed”

Both finasteride and GnRH agonist treatments reduced hair growth in women with idiopathic hirsutism, but GnRH agonist was more effective.

Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial

research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial

94 citations, January 2000 in “The Journal of Clinical Endocrinology and Metabolism”

Spironolactone most effective for hirsutism, but has side effects.

research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism

75 citations, October 1999 in “European journal of endocrinology”

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism

research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism

113 citations, April 1999 in “The Journal of Clinical Endocrinology and Metabolism”

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

research Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism

49 citations, June 1998 in “Journal of Endocrinological Investigation”

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

research Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism

76 citations, December 1997 in “Fertility and Sterility”

Finasteride reduces hair growth better, but spironolactone has more side effects.

Finasteride Cream in Hirsutism

Research cited in this study

research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism

research Comparison of Finasteride and Flutamide in the Treatment of Idiopathic Hirsutism

research Effect of Finasteride in Idiopathic Hirsutism

research Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism

research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up

research Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives

research A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women

research Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism

research Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women

research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

research Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men

research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque

research Treatment of Hirsutism with the Pure Antiandrogen Flutamide

research Ketoconazole Therapy for Women with Acne and/or Hirsutism

research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers

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Related Research

research The Efficacy and Use of Finasteride in Women: A Systematic Review

research Insulin Sensitizers for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials

research A randomized bilateral vehicle-controlled study of eflornithine cream combined with laser treatment versus laser treatment alone for facial hirsutism in women

research Randomized, double‐blind clinical evaluation of the efficacy and safety of topical eflornithine HCl 13.9% cream in the treatment of women with facial hair

research Hirsutism

research Comparison of High-Dose Finasteride (5 mg/day) Versus Low-Dose Finasteride (2.5 mg/day) in the Treatment of Hirsutism

research Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism

research Lack of Effect of Topical Finasteride Suggests an Endocrine Role for Dihydrotestosterone

research A Comparative Study of a Gonadotropin-Releasing Hormone Agonist and Finasteride on Idiopathic Hirsutism

research Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial

research Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism

research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism

research Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism

research Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism