TLDR The cream effectively and safely reduces facial hair in women.
The study conducted a randomized, double-blind clinical trial to evaluate the efficacy and safety of topical eflornithine HCl 13.9% cream for treating facial hair in women. The research involved a collaboration between Baylor College of Medicine, Gillette Advanced Technology Center, and Bristol-Myers Squibb. The results demonstrated that eflornithine HCl 13.9% cream was effective in reducing facial hair growth in women, providing a viable treatment option for this condition. The study also confirmed the safety of the cream, making it a promising solution for women seeking to manage unwanted facial hair.
64 citations,
May 2003 in “Journal of health psychology” Women with excess body hair feel psychological distress influenced by societal beauty standards, but distress isn't directly linked to the amount of hair.
5 citations,
June 1998 in “PubMed” Excessive androgen in women can cause acne, hair growth, baldness, and PCOS, often treatable with medication.
42 citations,
February 1996 in “Journal of Investigative Dermatology” Polyamines, especially spermidine, are essential for hair growth.
34 citations,
October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis”
September 2023 in “Pharmaceutics” The new face mask with Eflornithine can potentially reduce facial hair growth and moisturize skin.
66 citations,
September 2008 in “Dermatologic therapy” The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.
24 citations,
September 2014 in “Drug Delivery” Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.
August 2007 in “Drug and therapeutics bulletin” Eflornithine's effectiveness for women with facial hirsutism is unclear.
8 citations,
July 2012 in “Cambridge University Press eBooks” Androgens can both increase body hair and cause scalp hair loss.
27 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.