26 citations
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January 2012 in “Journal of the American Academy of Dermatology” This study found that adding topical eflornithine to hair laser treatment significantly reduced hair counts and inflammatory papules more effectively than laser therapy alone in treating pseudofolliculitis barbae.
24 citations
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September 2014 in “Drug Delivery” This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.
September 2023 in “Pharmaceutics” In this study, the authors developed a medicated face mask using electrospun fibers to deliver the active compound Eflornithine hydrochloride for managing hirsutism. The mask showed promising drug release characteristics, a high safety profile, and reduced hair growth in mice.
November 2021 in “SPAST Abstracts” In this study, EFH-SLM cream demonstrated greater efficiency in reducing hair density compared to plain EFH cream in Swiss albino female mice, with significantly less skin irritation and inflammation observed, suggesting improved permeability and effectiveness of EFH when using the new cream formulation.
133 citations
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July 2006 in “International Journal of Dermatology” This study found that topical eflornithine HCl 13.9% cream effectively reduced facial hair in women, with a favorable safety profile.