133 citations
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July 2006 in “International Journal of Dermatology” This study found that topical eflornithine HCl 13.9% cream effectively reduced facial hair in women, with a favorable safety profile.
115 citations
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January 2001 in “American journal of clinical dermatology” This study found that eflornithine 15% cream reduced unwanted facial hair growth more effectively than a placebo in women with hirsutism, but hair growth returned to pretreatment levels within 8 weeks of stopping treatment.
26 citations
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January 2012 in “Journal of the American Academy of Dermatology” This study found that adding topical eflornithine to hair laser treatment significantly reduced hair counts and inflammatory papules more effectively than laser therapy alone in treating pseudofolliculitis barbae.
5 citations
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June 2006 in “PubMed” This report presents a case of a woman with salt and pepper facial hair treated with a combination of laser hair removal and topical eflornithine.
July 2026 in “Journal of the Pakistan Medical Association” This study found that combining topical eflornithine with triple diode laser treatments in women with hirsutism led to a more rapid and nearly complete reduction of terminal hair after 6 months, though the intergroup differences were not significant at 6- and 12-month follow-ups.