Ketoconazole Therapy for Women with Acne and/or Hirsutism

    August 1990 in “ ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism ”
    Stefano Venturoli, Raffaella Fabbri, Luca Dal Prato, Barbara Mantovani, M. Capelli, Otello Magrini, Carlo Flamigni
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    TLDR Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
    In a study from 1990, 42 women with acne and/or hirsutism were treated with 400 mg/day of ketoconazole for 3-6 months. The treatment resulted in a decrease in androstenedione, total and free testosterone, 5 alpha dihydrotestosterone, and dehydroepiandrosterone levels, while 17 alpha hydroxyprogesterone, estradiol, ACTH, cortisol, LH, and FSH levels increased. Hair growth rate and diameter also decreased significantly. After 6 months, 14 subjects showed evident improvement in hirsutism, while 22 women who did not complete the therapy showed no significant change. Acne improved in all cases. However, side effects such as headache, nausea, hair loss, hepatitis, and biochemical changes were reported, indicating that ketoconazole treatment requires careful patient selection and monitoring.
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      community What ketoconazole shampoo do you use?

      in Ketoconazole  8 upvotes 3 days ago
      Nizoral is commonly used for hair loss and dandruff, but it can cause dryness; users often pair it with conditioners or alternative shampoos. Some also use finasteride, minoxidil, and red light therapy for hair care.

      community What ketoconazole shampoo do you use?

      in Ketoconazole  6 upvotes 4 weeks ago
      Users discuss ketoconazole shampoos for hair loss, mentioning Nizoral, selsun blue, and alternatives like prescription strength options and compounded lotions to reduce dryness. Some users suggest using finasteride and minoxidil instead, questioning the cost-benefit of ketoconazole.

      community Is Ketoconazole a big factor in preventing hairloss?

      in Ketoconazole  41 upvotes 1 month ago
      Ketoconazole shampoo may help with scalp health and inflammation but is not a substitute for DHT blockers like finasteride. It is generally considered a minor addition to hair loss treatment, with varying opinions on its effectiveness.

      community Ketoconazole shampoo stopping shed

      in Ketoconazole  11 upvotes 1 month ago
      The user experienced reduced hair shedding with Ketoconazole shampoo, suggesting it may help with scalp inflammation and hair health. They also use Minoxidil and Finasteride, and suspect food intolerance and stress contribute to their hair issues.

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