Histological Study of Reconstructed Hair Follicles

    August 2000 in “ Chinese Journal of Dermatology ”
    Lu Zhang, Jinjin Wu, Liu Rongqin, Baiyu Zhong, Shuqian Tang
    TLDR Dermal papilla cells can successfully grow and maintain hair follicles.
    The study investigated the potential of dermal papilla cells (DPC) to induce hair follicle regeneration and reconstruction. Using type I collagen gels populated with different cell types, including DPC, dermal sheath cells (DSC), and dermal fibroblasts, the researchers cultured these with epithelial cells from hair follicles. The results showed that hair follicle-like structures formed in cultures combining DPC with various follicle cells, and relatively intact hair follicles developed when these cultures were implanted into the subcutis of nude mice. The study concluded that DPC could effectively induce and sustain hair follicle growth both in vivo and in vitro.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Verteporfin and Microneedling

      in Treatments 5 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  732 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

    Related Research

    7 / 7 results