Hair Follicle Regeneration by Injection of Follicular Cells

January 2012 in “ PubMed ”

Xi-jin Sun, Zhiqi Hu, Yong Miao

hair follicle regeneration follicular cells epidermis dermis hair follicles dissociated cells nude mice blood vessels cyst black hairs implantation

TLDR Injecting follicular cells into skin can lead to the formation of new hair follicles.

The objective of this study was to investigate the mechanisms of hair follicle regeneration by injecting follicular cells isolated from mouse skin. The researchers peeled off the epidermis and digested the dermis to isolate hair follicles. These follicles were then digested into dissociated cells and injected into the skin of nude mice. The results showed that after injection, a cyst formed containing various cells and tissues. Over time, the skin thickened and hair follicles formed, accompanied by an increase in blood vessels. After several weeks, a cyst containing black hairs formed at the injection site. The study concluded that follicular cells can spontaneously aggregate and develop into hair follicles with a normal growth cycle after implantation. The success of regeneration depends on the interactions between follicular cells, recipient sites, and cell numbers.

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research Hair Follicle Regeneration by Injection of Follicular Cells

January 2012 in “PubMed”

Injecting follicular cells into skin can lead to the formation of new hair follicles.

research The Upper Dermal Sheath Has Potential to Regenerate Hair in Rat Follicular Epidermis

31 citations, September 1996 in “Differentiation”

The upper dermal sheath can regenerate hair in rats.