Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice

    June 2001 in “ Endocrinology ”
    A. J. Craven, Christopher J. Ormandy, Fiona G. Robertson … A. J. G. Pearson
    Studysummary In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.
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    Research cited in this study 5

    1. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    2. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    3. The Role of Prolactin in the Reactivation of Hair Follicles in Relation to Moulting in Cashmere Goats Journal of Endocrinology/Journal of endocrinology · 1994
    4. Does Prolactin Play a Role in Skin Biology and Pathology? Medical hypotheses · 1991
    5. Dermal-Epidermal Interactions in Hair Follicle Development and Cycling Clinics in dermatology · 1988