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    Glossary Prolactin Receptor

    protein on cell surfaces that binds to prolactin hormone

    The Prolactin Receptor (PRLR) is a protein found on the surface of certain cells that binds to the hormone prolactin. This interaction is crucial for various biological processes, including lactation, reproductive functions, and immune system regulation. In the context of hair biology, prolactin and its receptor can influence hair growth and hair cycle regulation.

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    Research 10 of 1000+

    1. Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen American Journal of Pathology · 2003 · 91 citations
    2. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice* Endocrinology · 2001 · 73 citations
    3. The prolactin receptor as a therapeutic target in human diseases: browsing new potential indications Expert Opinion on Therapeutic Targets · 2015 · 38 citations
    4. Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles <i>in vitro</i> British Journal of Dermatology · 2010 · 37 citations
    5. A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice Endocrinology · 2015 · 14 citations
    6. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice Endocrinology · 2001 · 14 citations
    7. Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women Reproductive Sciences · 2018 · 3 citations
    8. Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene Journal of Dairy Science · 2025 · 1 citations
    9. 1049 Novel strategy to promote hair follicle growth and stem cell activation in human male scalp skin: Targeting prolactin receptor with ABS-201 Journal of Investigative Dermatology · 2026
    10. Determining the Relationship Among Cattle Genotype, Hair Coat Score, and Productivity Through the Investigation of Single Nucleotide Polymorphisms within Prolactin, Dopamine Receptor D2, and Melatonin Receptor 1A 2019
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    Community 10 of 74

    1. Topical Tacrolimus For Androgenetic Alopecia (AGA) Reddit · 20 Sept 2026
    2. ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data Reddit · 23 Dec 2025
    3. Would you continue to use Finasteride and Minoxidil once HMI 115 becomes available? Reddit · 24 May 2024
    4. PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance Reddit · 27 Nov 2023
    5. HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia Reddit · 28 Oct 2023
    6. What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news Reddit · 2 Dec 2025
    7. A New Hair Loss Drug Could Cure Balding and Reverse Graying Reddit · 21 Oct 2025
    8. Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently. Reddit · 21 Dec 2023
    9. MPB - Has anyone else seen this video on ABS-201? Reddit · 23 Sept 2026
    10. How to know if shedding is from tren or minoxidil? Reddit · 29 Mar 2024
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    Learn 1

    1. HMI-115 Experimental antibody that blocks the prolactin receptor