A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice

    August 2015 in “ Endocrinology ”
    Christiane Otto, Anna Särnefält, Anne Ljungars … Christoph Freiberg
    Studysummary This study describes the development of a monoclonal antibody, 005-C04, which blocks PRLR-mediated signaling, suggesting its potential for furthering understanding of PRLR's role in health and disease.
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    Research cited in this study 2

    1. Prolactin Delays Hair Regrowth in Mice Journal of Endocrinology · 2006
    2. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice Endocrinology · 2001