75 citations
,
March 1998 in “Journal of Investigative Dermatology” This study reports that transgenic mice carrying Clone B DNA developed spontaneous melanomas likely due to an interruption in genes regulating cell growth in melanin-producing cells, offering a model for melanoma research.
9 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identifies novel subpopulations of human epidermal melanocytes and specific transcriptional programs that differ from model organisms, providing insights into melanoma dedifferentiation.
17 citations
,
May 2018 in “Journal of Biomedical Optics” This review discusses how the optical properties of human hair might contribute to melanoma development but reports no new experimental findings, suggesting further research is needed to support this hypothesis.
5 citations
,
June 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that applying topical thymidine dinucleotide (pTT) to newborn mice before UV exposure delayed and reduced melanoma development compared to untreated controls.
April 2018 in “Journal of Investigative Dermatology” This study found that no patients with moderately dysplastic nevi with positive margins developed melanoma at the biopsy site, but those with a history of multiple nevi may have a higher risk of melanoma elsewhere.