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    Glossary CXCL1

    small protein that attracts white blood cells to inflammation

    CXCL1, also known as Chemokine (C-X-C motif) ligand 1 or GROα, is a small protein involved in the immune response. It acts as a signaling molecule that attracts white blood cells to sites of inflammation or injury, playing a crucial role in wound healing and immune defense. In the context of hair biology, CXCL1 can influence hair follicle cycling and may be involved in conditions like alopecia, where hair loss occurs.

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    1. The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles Differentiation · 2009 · 57 citations
    2. CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17 The Journal of Experimental Medicine · 2024 · 32 citations
    3. Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata Annals of Dermatology · 2019 · 17 citations
    4. Polymorphisms in the promoter regions of the CXCL1 and CXCL2 genes contribute to increased risk of alopecia areata in the Korean population Genetics and Molecular Research · 2015 · 8 citations
    5. Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing Frontiers in Immunology · 2024 · 7 citations
    6. Combination of an engineered <i>Lactococcus lactis</i> expressing CXCL12 with light‐emitting diode yellow light as a treatment for scalded skin in mice Microbial biotechnology · 2021 · 6 citations
    7. Th1 Chemokine CXCL10 and Alopecia Areata: The Possible Target for the Treatment of Alopecia Areata Journal of Clinical & Cellular Immunology · 2016 · 3 citations
    8. Proteomic Predictors of Baricitinib Response in Severe Alopecia Areata: CCL11 Flags a Refractory Phenotype 2025
    9. CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata International Journal of Molecular Sciences · 2024
    10. CXCL12 inhibits hair growth through CXCR4 Biomedicine & Pharmacotherapy · 2022
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