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GlossaryCXCL9

chemokine that attracts immune cells to inflammation sites

CXCL9, also known as Monokine Induced by Gamma Interferon (MIG), is a type of chemokine—a small signaling protein involved in the immune response. It plays a crucial role in attracting immune cells, particularly T-cells, to sites of inflammation or infection. This chemokine is often studied in the context of autoimmune diseases and inflammatory conditions, including alopecia areata, where it can contribute to the immune system's attack on hair follicles.

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research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins

2 citations , April 2018 in “Journal of Investigative Dermatology”

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

research Elevation of Circulating DNAs of Disease-Associated Cytokines in Serum Cell-Free DNA from Patients with Alopecia Areata

April 2024 in “Bioscience trends”

Higher levels of certain DNAs in blood may indicate hair follicle damage in alopecia areata patients.

research Gene Expression Signatures and ALADIN Score Correlate with Response of Alopecia Areata Patients to Treatment with JAK Inhibitors

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

The ALADIN score can predict how well patients with alopecia areata will respond to JAK inhibitor treatments.

research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences

April 2024 in “International journal of molecular sciences”

Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.

research Morphea: Progress to Date and the Road Ahead

50 citations , March 2021 in “Annals of Translational Medicine”

More research is needed to understand and treat morphea effectively.

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community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 2 years ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Seriously confused about minoxidil's method of action

in Minoxidil 6 upvotes 3 years ago

The conversation discusses confusion about how Minoxidil promotes hair growth compared to other substances like Menthol, which have similar actions. The user mentions personal positive results with peppermint oil extract and is currently trying L-citrulline for its vasodilation effects.

community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

MagicBold in Treatments 309 upvotes 1 year ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community Stop expecting results in 2 months!

in Treatment 125 upvotes 1 year ago

People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 7 upvotes 1 year ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

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