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    Glossary CXCL9

    chemokine that attracts immune cells to inflammation sites

    CXCL9, also known as Monokine Induced by Gamma Interferon (MIG), is a type of chemokine—a small signaling protein involved in the immune response. It plays a crucial role in attracting immune cells, particularly T-cells, to sites of inflammation or infection. This chemokine is often studied in the context of autoimmune diseases and inflammatory conditions, including alopecia areata, where it can contribute to the immune system's attack on hair follicles.

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    1. Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata Annals of Dermatology · 2019 · 17 citations
    2. CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata International Journal of Molecular Sciences · 2024
    3. CXCL12 inhibits hair growth through CXCR4 Biomedicine & Pharmacotherapy · 2022
    4. The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles Differentiation · 2009 · 57 citations
    5. CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17 The Journal of Experimental Medicine · 2024 · 32 citations
    6. Polymorphisms in the promoter regions of the CXCL1 and CXCL2 genes contribute to increased risk of alopecia areata in the Korean population Genetics and Molecular Research · 2015 · 8 citations
    7. Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing Frontiers in Immunology · 2024 · 7 citations
    8. Combination of an engineered <i>Lactococcus lactis</i> expressing CXCL12 with light‐emitting diode yellow light as a treatment for scalded skin in mice Microbial biotechnology · 2021 · 6 citations
    9. Th1 Chemokine CXCL10 and Alopecia Areata: The Possible Target for the Treatment of Alopecia Areata Journal of Clinical & Cellular Immunology · 2016 · 3 citations
    10. Insights into the context-dependent immunological roles of the CXCL12–CXCR4 axis in alopecia Frontiers in Immunology · 2026
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