Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences

    April 2024 in “ International journal of molecular sciences ”
    Hitoshi Yamaguchi, Yuji Yamaguchi, Elena Peeva
    Studysummary This study examines the similarities and differences in the pathogenesis of autoimmune conditions alopecia areata and vitiligo, highlighting shared features like immune cell involvement and cytokine pathways, while noting differing immune responses in skin and hair.
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    Research cited in this study 26

    1. European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2024
    2. Involvement of DKK1 Secreted From Adipose-Derived Stem Cells in Alopecia Areata Cell Proliferation · 2023
    3. Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions Frontiers in immunology · 2023
    4. Alopecia Areata: Current Treatments and New Directions American Journal of Clinical Dermatology · 2023
    5. Comorbid Conditions Associated With Alopecia Areata: A Systematic Review and Meta-Analysis American Journal of Clinical Dermatology · 2023
    6. Functional Interrogation of Lymphocyte Subsets in Alopecia Areata Using Single-Cell RNA Sequencing Proceedings of the National Academy of Sciences · 2023
    7. Serum Brain-Derived Neurotrophic Factor and Vitamin D: Two Concordant Players Controlling Depression Among Alopecia Areata and Vitiligo Patients: A Case-Control Study Journal of Cosmetic Dermatology · 2023
    8. Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity: Lessons from Alopecia Areata eLife · 2023
    9. Scalp Biomarkers During Dupilumab Treatment Support Th2 Pathway Pathogenicity in Alopecia Areata Allergy · 2022
    10. Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implications of Post-Translational Modifications Frontiers in immunology · 2022
    11. Resident Memory T Cells in Autoimmune Skin Diseases Frontiers in immunology · 2021
    12. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    13. A Large Cross-Sectional Survey Study of the Prevalence of Alopecia Areata in the United States Clinical Cosmetic and Investigational Dermatology · 2020
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    16. Dickkopf-1 Expression in Androgenetic Alopecia and Alopecia Areata in Male Patients American Journal of Dermatopathology · 2019
    17. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017
    18. Understanding Autoimmunity of Vitiligo and Alopecia Areata Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics · 2016
    19. Assessment of Tissue Levels of Dickkopf-1 in Androgenetic Alopecia and Alopecia Areata Journal of Cosmetic Dermatology · 2015
    20. Plasmacytoid Dendritic Cells in Alopecia Areata: Missing Link? Journal of the European Academy of Dermatology and Venereology · 2014
    21. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    22. Vitiligo and Alopecia Areata: Apples and Oranges? Experimental Dermatology · 2013
    23. Epitopes, Avidity, and IgG Subclasses of Tyrosine Hydroxylase Autoantibodies in Vitiligo and Alopecia Areata Patients British Journal of Dermatology · 2012
    24. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    25. Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata Journal of Clinical Investigation · 2007
    26. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007

    Related research 1

    1. Serum Zinc Concentration in Patients With Alopecia Areata Acta dermato-venereologica (Print) · 2023