European Expert Consensus Statement on the Systemic Treatment of Alopecia Areata

    January 2024 in “ JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology ”
    Lidia Rudnicka, Monika Arenbergerová, Ramón Grimalt … Anna Waśkiel‐Burnat
    Studysummary This consensus statement outlines a treatment algorithm for alopecia areata, detailing systemic treatment indications and options, including EMA-approved medications baricitinib and ritlecitinib for severe cases, as well as other off-label treatments and adjuvant therapies like oral minoxidil.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 33

    1. Diagnosis And Management Of Alopecia Areata: A Saudi Expert Consensus Statement (2023) Dermatology and Therapy · 2023
    2. Major Improvement of Very Severe Alopecia Areata in Patients Treated With the Combination of Baricitinib and Low Doses of Corticosteroids: An Eight-Case Series Clinical and Experimental Dermatology · 2023
    3. Efficacy and Safety of Ritlecitinib in Adolescents with Alopecia Areata: Results from the ALLEGRO Phase 2b/3 Randomized, Double-Blind, Placebo-Controlled Trial Pediatric Dermatology · 2023
    4. Janus Kinase Inhibitors For Alopecia Areata JAMA network open · 2023
    5. The Evaluation of JAK Inhibitors on Effect and Safety in Alopecia Areata: A Systematic Review and Meta-Analysis of 2018 Patients Frontiers in immunology · 2023
    6. Trichoscopy Patterns in Alopecia Areata: A Systematic Review and Meta-Analysis Skin Research and Technology · 2023
    7. Safety of Janus Kinase Inhibitors in Patients with Alopecia Areata: A Systematic Review Clinical drug investigation · 2023
    8. Efficacy and Safety of Different JAK Inhibitors in the Treatment of Alopecia Areata: A Network Meta-Analysis Frontiers in immunology · 2023
    9. Efficacy and Safety of Ritlecitinib in Adults and Adolescents With Alopecia Areata: A Randomised, Double-Blind, Multicentre, Phase 2b–3 Trial The Lancet · 2023
    10. The Burden of Alopecia Areata: A Scoping Review Focusing on Quality of Life, Mental Health, and Work Productivity Journal of the European Academy of Dermatology and Venereology · 2023
    11. Alopecia Areata: Diagnostic and Therapeutic Recommendations of the Polish Society of Dermatology. Part 2: Treatment Przegląd Dermatologiczny · 2023
    12. Alopecia Areata: Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society, Part 1: Diagnosis and Severity Assessment Przegla̧d dermatologiczny · 2023
    13. Alopecia Areata and Risk of Atopic and Autoimmune Conditions: Population-Based Cohort Study Clinical and Experimental Dermatology · 2022
    14. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    15. Oral Tofacitinib and Systemic Corticosteroids, Alone or in Combination, in Patients With Moderate-to-Severe Alopecia Areata: A Retrospective Study Frontiers in Medicine · 2022
    16. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    17. Alopecia Areata: Current Understanding and Management Journal der Deutschen Dermatologischen Gesellschaft · 2022
    18. Maintenance, Withdrawal, and Re-Treatment with Ritlecitinib and Brepocitinib in Patients with Alopecia Areata in a Single-Blind Extension of a Phase 2a Randomized Clinical Trial Journal of the American Academy of Dermatology · 2021
    19. A Phase 2a Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of the Oral Janus Kinase Inhibitors Ritlecitinib and Brepocitinib in Alopecia Areata: 24-Week Results Journal of the American Academy of Dermatology · 2021
    20. Utility of Azathioprine, Methotrexate, and Cyclosporine as Steroid-Sparing Agents in Chronic Alopecia Areata: A Retrospective Study of Continuation Rates in 138 Patients JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2020
    21. Cyclosporine With and Without Systemic Corticosteroids in Treatment of Alopecia Areata: A Systematic Review Dermatology and therapy · 2020
    22. Alopecia Areata Predictive Score: A New Trichoscopy-Based Tool to Predict Treatment Outcome in Patients with Patchy Alopecia Areata Journal of Cosmetic Dermatology · 2019
    23. Treatment of Alopecia Areata: An Australian Expert Consensus Statement Australasian journal of dermatology · 2018
    24. Trichoscopy of Alopecia Areata: An Update The Journal of Dermatology · 2018
    25. Alopecia Areata: A Comprehensive Review of Pathogenesis and Management Clinical Reviews in Allergy & Immunology · 2017
    26. Methotrexate for the Treatment of Pediatric Alopecia Areata Journal of dermatological treatment · 2017
    27. Late-Onset Alopecia Areata: A Retrospective Cohort Study Dermatology · 2017
    28. Pulse Corticosteroid Therapy With Oral Dexamethasone for the Treatment of Adult Alopecia Totalis and Universalis Journal of the American Academy of Dermatology · 2016
    29. Efficacy and Safety of Methotrexate Combined with Low- to Moderate-Dose Corticosteroids for Severe Alopecia Areata Dermatology · 2016
    30. Efficacy and Safety of Methotrexate in Alopecia Areata Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia · 2014
    31. Alopecia Areata Update Dermatologic Clinics · 2012
    32. Efficacy and Tolerability of Methotrexate in Severe Childhood Alopecia Areata British journal of dermatology/British journal of dermatology, Supplement · 2011
    33. Placebo-Controlled Oral Pulse Prednisolone Therapy in Alopecia Areata Journal of the American Academy of Dermatology · 2005

    Related research 6

    1. Case Report of Novel Combination of Anthralin and Calcipotriene Leading to Trichologic Response in Alopecia Areata JAAD case reports · 2019
    2. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    3. Linear Alopecia Areata JAAD case reports · 2018
    4. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    5. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    6. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013