Cyclosporine With and Without Systemic Corticosteroids in Treatment of Alopecia Areata: A Systematic Review

    April 2020 in “ Dermatology and therapy ”
    Joanna Nowaczyk, Karolina Makowska, Adriana Rakowska … Lidia Rudnicka
    Studysummary This systematic review assessed cyclosporine's effectiveness with or without corticosteroids for treating alopecia areata, finding combined therapy more effective and with a lower recurrence rate than monotherapy, especially for severe cases, though results varied by alopecia type.
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    Research cited in this study 19

    1. Cyclosporine for Moderate-to-Severe Alopecia Areata: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of Efficacy and Safety Journal of the American Academy of Dermatology · 2019
    2. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    3. JAK Inhibitors and Alopecia Areata Lancet · 2019
    4. A Comparative Study of Oral Cyclosporine and Betamethasone Minipulse Therapy in the Treatment of Alopecia Areata Annals of dermatology/Annals of Dermatology · 2016
    5. Comparison of High-Dose Corticosteroid Pulse Therapy and Combination Therapy Using Oral Cyclosporine with Low-Dose Corticosteroid in Severe Alopecia Areata Annals of dermatology/Annals of Dermatology · 2015
    6. Current Treatment of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013
    7. The Effect of Oral Cyclosporine in the Treatment of Severe Alopecia Areata Cutaneous and ocular toxicology · 2013
    8. Alopecia Areata: A Review Journal of the Saudi Society of Dermatology & Dermatologic Surgery · 2013
    9. Alopecia Areata: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    10. The Genetics of Alopecia Areata: What's New and How Will It Help Our Patients? Dermatologic therapy · 2011
    11. Etiopathogenesis of Alopecia Areata: Why Do Our Patients Get It? Dermatologic therapy · 2011
    12. The Use of Cyclosporine in Dermatology: Part I Journal of the American Academy of Dermatology · 2010
    13. Alopecia Areata Update Journal of the American Academy of Dermatology · 2010
    14. Topical Immunotherapy in Alopecia Areata International journal of trichology · 2010
    15. Treatment of Severe Alopecia Areata: Combination Therapy Using Systemic Cyclosporine A with Low Dose Corticosteroids Annals of Dermatology · 2008
    16. Alopecia Areata: Overview and Treatment Options International Journal of Dermatology · 2007
    17. Melanocyte and Gonad Activity as Potential Severity Modifying Factors in C3H/HeJ Mouse Alopecia Areata Experimental dermatology · 2001
    18. Partial Response of Severe Alopecia Areata to Cyclosporine A Dermatology · 1999
    19. Alopecia Universalis Treated With Oral Cyclosporine A And Prednisolone: Immunologic Studies International Journal of Dermatology · 1992

    Related research 5

    1. Case Report of Novel Combination of Anthralin and Calcipotriene Leading to Trichologic Response in Alopecia Areata JAAD case reports · 2019
    2. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    3. Linear Alopecia Areata JAAD case reports · 2018
    4. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    5. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013