Treatment of Severe Alopecia Areata: Combination Therapy Using Systemic Cyclosporine A with Low Dose Corticosteroids

    January 2008 in “ Annals of Dermatology ”
    Deborah Lee, Doo Jin Oh, Jung‐Wook Kim … Seon Wook Hwang
    Studysummary This study concluded that combining systemic cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata while maintaining safe cyclosporine A levels in the blood.
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    Research cited in this study 9

    1. A Comparison of the Efficacy, Relapse Rate, and Side Effects Among Three Modalities of Systemic Corticosteroid Therapy for Alopecia Areata Dermatology · 2006
    2. Placebo-Controlled Oral Pulse Prednisolone Therapy in Alopecia Areata Journal of the American Academy of Dermatology · 2005
    3. Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis Journal of the American Academy of Dermatology · 2003
    4. Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes American Journal of Physiology-cell Physiology · 2003
    5. Cyclosporine Combination Therapy in Alopecia Areata Linchuang pifuke zazhi · 2002
    6. Partial Response of Severe Alopecia Areata to Cyclosporine A Dermatology · 1999
    7. Efficacy of Topical Sensitizers in the Treatment of Alopecia Areata Journal of the American Academy of Dermatology · 1998
    8. Severe Alopecia Areata Treated With Systemic Corticosteroids International Journal of Dermatology · 1998
    9. Alopecia Universalis Treated With Oral Cyclosporine A And Prednisolone: Immunologic Studies International Journal of Dermatology · 1992

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