Treatment of Severe Alopecia Areata: Combination Therapy Using Systemic Cyclosporine A with Low Dose Corticosteroids

January 2008 in “ Annals of Dermatology ”

Deborah Lee, Doo Jin Oh, Jung‐Wook Kim, Sung Wook Park, Min Kyung Oh, Ho Suk Sung, Seon Wook Hwang

TLDR Combining Cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata.

The study concluded that the combination therapy of systemic Cyclosporine A (CsA) with low-dose corticosteroids was effective in treating severe alopecia areata (AA). This approach resulted in achieving a safe, therapeutic concentration of CsA in the peripheral blood, indicating its potential as a viable treatment option for severe cases of AA.

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Treatment of Severe Alopecia Areata: Combination Therapy Using Systemic Cyclosporine A with Low Dose Corticosteroids

Research cited in this study

research A Comparison of the Efficacy, Relapse Rate, and Side Effects Among Three Modalities of Systemic Corticosteroid Therapy for Alopecia Areata

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research Clobetasol Propionate 0.05% Under Occlusion in the Treatment of Alopecia Totalis/Universalis

research Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes

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