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GlossaryCyclosporine (CsA)

immunosuppressive drug used to prevent organ rejection and treat autoimmune diseases

Cyclosporine, also known as cyclosporin A or CsA, is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune conditions. It works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. In dermatology, cyclosporine has been explored for its potential to treat severe cases of alopecia areata, a condition characterized by sudden hair loss.

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Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles

research Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles

68 citations , May 2018 in “PLOS Biology”

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

research Cyclosporine A-Induced Intracranial Thrombotic Complications: Systematic Review and Case Report

6 citations , February 2021 in “Frontiers in Neurology”

Cyclosporine-A can cause serious blood clots in the brain, so patients need careful monitoring.

research Long-Term Survival of Skin Allografts in Rats Treated with Topical Cyclosporine

22 citations , July 1987 in “Transplantation”

Topical cyclosporine significantly extends skin graft survival in rats.

research Effect of Immunosuppressive PPIase Inhibitors, Cyclosporin A, FK506, Ascomycin, and Rapamycin on Hair Growth Initiation

August 1994 in “Journal of dermatological science”

Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.

research Cyclosporin A Suppresses TGF-Beta2 Expression Via Calcineurin/NFAT Pathway in Human Dermal Papilla Cells

April 2023 in “Journal of Investigative Dermatology”

Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.

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community Huge Group Buy is Now Live with New and Existing Treatments

in Product 146 upvotes 2 years ago

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.

community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 10 months ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

community I will never more buy any hairloss traitements in public pharmacy

in Minoxidil 420 upvotes 1 year ago

A user was embarrassed by a pharmacist's loud mention of "minoxidil" for hair loss, sparking a discussion on the stigma and unprofessionalism. Users suggested online purchases or different pharmacies for privacy and reassured that most people don't notice others' purchases.

community The DEFINITIVE cure for hairloss

in Satire 270 upvotes 9 months ago

The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.

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